中国现代药物应用
中國現代藥物應用
중국현대약물응용
CHINESE JOURNAL OF MODERN DRUG APPLICATION
2014年
11期
20-21,22
,共3页
美托洛尔%稳心颗粒%频发性室性早搏
美託洛爾%穩心顆粒%頻髮性室性早搏
미탁락이%은심과립%빈발성실성조박
Metoprolol%Wenxin Granule%Frequent premature ventricular contractions
目的：观察并对比稳心颗粒联合小剂量美托洛尔与单独用稳心颗粒治疗频发性室性早搏的临床效果，并评价其安全性。方法选择本院2013年1月~2014年1月收治的频发性室性早搏患者58例，随机分成两组，单独服用稳心颗粒患者为对照组，稳心颗粒联合小剂量美托洛尔服用者为治疗组。2个疗程治疗后，观察临床疗效、24 h动态心电图的变化及不良反应发生情况。结果与治疗前相比，单独服用稳心颗粒与稳心颗粒联合小剂量美托洛尔服用对治疗频发性室性早搏均有明显疗效，对照组总有效率为73.2%，治疗组总有效率为96.7%，与对照组相比差异有统计学意义(P<0.05)；且治疗组24 h室性早搏次数明显下降，与对照组相比差异有统计学意义(P<0.05)；两组患者均未发现明显副反应。结论
目的：觀察併對比穩心顆粒聯閤小劑量美託洛爾與單獨用穩心顆粒治療頻髮性室性早搏的臨床效果，併評價其安全性。方法選擇本院2013年1月~2014年1月收治的頻髮性室性早搏患者58例，隨機分成兩組，單獨服用穩心顆粒患者為對照組，穩心顆粒聯閤小劑量美託洛爾服用者為治療組。2箇療程治療後，觀察臨床療效、24 h動態心電圖的變化及不良反應髮生情況。結果與治療前相比，單獨服用穩心顆粒與穩心顆粒聯閤小劑量美託洛爾服用對治療頻髮性室性早搏均有明顯療效，對照組總有效率為73.2%，治療組總有效率為96.7%，與對照組相比差異有統計學意義(P<0.05)；且治療組24 h室性早搏次數明顯下降，與對照組相比差異有統計學意義(P<0.05)；兩組患者均未髮現明顯副反應。結論
목적：관찰병대비은심과립연합소제량미탁락이여단독용은심과립치료빈발성실성조박적림상효과，병평개기안전성。방법선택본원2013년1월~2014년1월수치적빈발성실성조박환자58례，수궤분성량조，단독복용은심과립환자위대조조，은심과립연합소제량미탁락이복용자위치료조。2개료정치료후，관찰림상료효、24 h동태심전도적변화급불량반응발생정황。결과여치료전상비，단독복용은심과립여은심과립연합소제량미탁락이복용대치료빈발성실성조박균유명현료효，대조조총유효솔위73.2%，치료조총유효솔위96.7%，여대조조상비차이유통계학의의(P<0.05)；차치료조24 h실성조박차수명현하강，여대조조상비차이유통계학의의(P<0.05)；량조환자균미발현명현부반응。결론
Objective To study and contrast the curative effect of Wenxin Granule combined with small doses of metoprolol in the treatment of patients with frequent premature ventricular contractions, and evaluate the safety of the drugs. Methods Choosing 58 patients with frequent premature ventricular contractions treated in our hospital from January 2013 to January 2014 and dividing them into two groups randomly. The control group was only treated with Wenxin Granule, the experimental group was given Wenxin Granule combined with small doses of metoprolol. After two courses of treatment, the curative effect was assessed by the change of 24 h dynamic electrocardiogram and the adverse reactions. Results Compared with pre-treatment, both treatment with Wenxin Granule alone and combined with small doses of metoprolol was effectively to patients with frequent premature ventricular contractions. The total effective rate of control group was 73.2%, and the experiment group was 96.7%, significantly higher than control group(P<0.05). The ventricular premature beat frequency in 24 h of the experiment group was significantly decreased, there was significantly difference compared with control group (P<0.05). There was no obvious adverse reaction in patients of the two groups. Conclusion The curative effect of Wenxin Granule combined with small doses of metoprolol in the treatment of frequent premature ventricular contractions is better than Wenxin Granule alone. There is no adverse reaction, so it is worthy of clinical promotion.
