海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
11期
1613-1615
,共3页
王雪飞%罗漫灵%汪丽萍%钟梅
王雪飛%囉漫靈%汪麗萍%鐘梅
왕설비%라만령%왕려평%종매
胎膜早破%绒毛膜羊膜炎%宫内感染%新生儿窒息%缺血缺氧性脑病
胎膜早破%絨毛膜羊膜炎%宮內感染%新生兒窒息%缺血缺氧性腦病
태막조파%융모막양막염%궁내감염%신생인질식%결혈결양성뇌병
Premature rupture of membranes (PROM)%Chorioamnionitis%Intrauterine infection%Neonatal as-phyxia%Hypoxic Ischemic Encephalopathy (HIE)
目的：探讨胎膜早破患者胎盘病理与新生儿预后的相关性，评估胎盘病理对新生儿预后的意义。方法回顾性分析2012年1月1日至2012年12月31日在我院分娩的454例胎膜早破患者的胎盘病理情况及新生儿结局，根据产后胎盘病理将其分成正常、轻度、中度、重度以及慢性绒毛膜羊膜炎症等5组，比较各组间孕产妇分娩前白细胞、C反应蛋白、新生儿窒息发生率、新生儿娩出当日白细胞、C反应蛋白的差异。结果胎盘病理表现为正常、轻度、中度、重度以及慢性绒毛膜羊膜炎组新生儿窒息率分别为10.47%、11.94%、10%、37.5%、28.57%，各组间差异有统计学意义(P=0.003)；新生儿娩出当日CRP分别为(0.21±0.58) mg/L、(0.26±0.66) mg/L、(6.2±19.0) mg/L、(9.6±15.4) mg/L、(0.0±0.0) mg/L，白细胞分别为(10.7±2.84)×109/L、(10.2±3.45)×109/L、（17.6±5.57）×109/L、(22.9±14.6)×109/L、（12.8±8.05）×109/L，进行两两比较，发现胎盘病理呈现重度绒毛膜羊膜炎的孕产妇，新生儿娩出当日CRP、白细胞均显著高于其他各组(P＜0.05)。结论胎膜早破患者胎盘病理类型与新生儿预后存在一定相关性，重度绒毛膜羊膜炎可能预示新生儿预后不良。
目的：探討胎膜早破患者胎盤病理與新生兒預後的相關性，評估胎盤病理對新生兒預後的意義。方法迴顧性分析2012年1月1日至2012年12月31日在我院分娩的454例胎膜早破患者的胎盤病理情況及新生兒結跼，根據產後胎盤病理將其分成正常、輕度、中度、重度以及慢性絨毛膜羊膜炎癥等5組，比較各組間孕產婦分娩前白細胞、C反應蛋白、新生兒窒息髮生率、新生兒娩齣噹日白細胞、C反應蛋白的差異。結果胎盤病理錶現為正常、輕度、中度、重度以及慢性絨毛膜羊膜炎組新生兒窒息率分彆為10.47%、11.94%、10%、37.5%、28.57%，各組間差異有統計學意義(P=0.003)；新生兒娩齣噹日CRP分彆為(0.21±0.58) mg/L、(0.26±0.66) mg/L、(6.2±19.0) mg/L、(9.6±15.4) mg/L、(0.0±0.0) mg/L，白細胞分彆為(10.7±2.84)×109/L、(10.2±3.45)×109/L、（17.6±5.57）×109/L、(22.9±14.6)×109/L、（12.8±8.05）×109/L，進行兩兩比較，髮現胎盤病理呈現重度絨毛膜羊膜炎的孕產婦，新生兒娩齣噹日CRP、白細胞均顯著高于其他各組(P＜0.05)。結論胎膜早破患者胎盤病理類型與新生兒預後存在一定相關性，重度絨毛膜羊膜炎可能預示新生兒預後不良。
목적：탐토태막조파환자태반병리여신생인예후적상관성，평고태반병리대신생인예후적의의。방법회고성분석2012년1월1일지2012년12월31일재아원분면적454례태막조파환자적태반병리정황급신생인결국，근거산후태반병리장기분성정상、경도、중도、중도이급만성융모막양막염증등5조，비교각조간잉산부분면전백세포、C반응단백、신생인질식발생솔、신생인면출당일백세포、C반응단백적차이。결과태반병리표현위정상、경도、중도、중도이급만성융모막양막염조신생인질식솔분별위10.47%、11.94%、10%、37.5%、28.57%，각조간차이유통계학의의(P=0.003)；신생인면출당일CRP분별위(0.21±0.58) mg/L、(0.26±0.66) mg/L、(6.2±19.0) mg/L、(9.6±15.4) mg/L、(0.0±0.0) mg/L，백세포분별위(10.7±2.84)×109/L、(10.2±3.45)×109/L、（17.6±5.57）×109/L、(22.9±14.6)×109/L、（12.8±8.05）×109/L，진행량량비교，발현태반병리정현중도융모막양막염적잉산부，신생인면출당일CRP、백세포균현저고우기타각조(P＜0.05)。결론태막조파환자태반병리류형여신생인예후존재일정상관성，중도융모막양막염가능예시신생인예후불량。
Objective To study the correlation between placental pathology and neonatal in patients with pre-mature rupture of membranes (PROM). Methods The data of chorioamnionitis and the newborns outcomes in 454 patients with PROM who labored in NanFang hosipital from Jan 2012 to Dec 2012 were analyzed rettrospectively. Ac-cording to the pathology results of placenta, the patients were divided into normal, mild, moderate, severe and chronic chorioamnionitis groups. Antepartum maternal WBC, CRP, neonatal asphyxia ratio, leukocyte and CRP of newboens of those groups were compared. Results The neonatal asphyxia ratio of normal, mild, moderate, severe and chron-ic chorioamnionitis groups were 10.47%, 11.94%, 10%, 37.5%, 28.57%, respectively, and the differences among them showed statistically significant. The CRP concentration of newborns of those groups were (0.21 ± 0.58) mg/L, (0.26±0.66) mg/L, (6.2±19.0) mg/L, (9.6±15.4) mg/L and (0.0±0.0) mg/L, respectively. The WBC of newborns of those groups were (10.7±2.84)×109/L, (10.2±3.45)×109/L, (17.6±5.57)×109/L, (22.9±14.6)×109/L and (12.8±8.05)×109/L, re-spectively. The CRP and the WBC of newborns in chorioamnionitis group were significantly higher than those of oth-er groups. Conclusion There is a close correlation between Chorioamnionitis and the newborns outcomes, and the occurence of severe chorioamnionitis may indicate poor prognosis of newborns.
