CAJ | 학술논문

观察基质金属蛋白酶-7(matrix metal oproteinase-7 MMP-7)在子宫内膜癌组织中的表达及其与子宫内膜癌组织学分级和临床分期的关系。方法检测256例子宫内膜癌组织中M M P-7的蛋白定位表达水平并结合临床病理特征进行分析。结果子宫内膜癌中M M P-7表达明显增高( P＜0.05)，并与癌组织手术-病理分期和组织学分级密切相关。结论 MMP-7参与子宫内膜癌的侵袭和转移，有望成为子宫内膜癌发展及预后判断的一种新的参考指标。
관찰기질금속단백매-7(matrix metal oproteinase-7 MMP-7)재자궁내막암조직중적표체급기여자궁내막암조직학분급화림상분기적관계。방법검측256례자궁내막암조직중M M P-7적단백정위표체수평병결합림상병리특정진행분석。결과자궁내막암중M M P-7표체명현증고( P＜0.05)，병여암조직수술-병리분기화조직학분급밀절상관。결론 MMP-7삼여자궁내막암적침습화전이，유망성위자궁내막암발전급예후판단적일충신적삼고지표。
Objective Observation matrix metal oproteinase - 7 in endometrial carcinoma tissue and its expression of endometrial carcinoma histological grading and the relationship between the clinical stage. Methods Testing 256 example palace film carcinoma tissues MMP - 7 protein localization expression level and combined with clinical and pathological features were analyzed. Results Endometrial carcinoma of MMP - 7 express increased obviously(P<0.05),And with cancer tissue surgery - pathological stage and histological grading closely related. Conclusion MMP - to participate in endometrial cancer invasion and metastasis, is expected to become a new reference index of endometrial cancer development and prognostic.