世界最新医学信息文摘(电子版)
世界最新醫學信息文摘(電子版)
세계최신의학신식문적(전자판)
World Latest Medicine Information
2014年
13期
46-46,50
,共2页
抗凝治疗%不稳定型心绞痛%临床观察
抗凝治療%不穩定型心絞痛%臨床觀察
항응치료%불은정형심교통%림상관찰
anticoagulant therapy%unstable angina%clinical observation
目的:观察低分子肝素钠并联用氯吡格雷、拜阿司匹林治疗不稳定型心绞痛(Ua)的临床疗效。方法患者70例,男性57例,女性13例,年龄45~76(56.1±10.80)岁。随机分为对照组35例,给予氯吡格雷、拜阿司匹林口服。治疗组35例,在对照组基础上加用低分子肝素钠(克赛),每12小时皮下注射,疗程7天,观察4周。结果治疗组总有效率97%,对照组总有效率71.3%,两组比较差异性显著(P<0.05)。治疗组无1例发生心肌梗塞,对照组发生1例(3%)。治疗组无明显不良反应。结论在双联抗血小板治疗基础上加用低分子肝素钠,能有效的控制不稳定型心绞痛(Ua)发作,减少心肌梗塞的发生。
目的:觀察低分子肝素鈉併聯用氯吡格雷、拜阿司匹林治療不穩定型心絞痛(Ua)的臨床療效。方法患者70例,男性57例,女性13例,年齡45~76(56.1±10.80)歲。隨機分為對照組35例,給予氯吡格雷、拜阿司匹林口服。治療組35例,在對照組基礎上加用低分子肝素鈉(剋賽),每12小時皮下註射,療程7天,觀察4週。結果治療組總有效率97%,對照組總有效率71.3%,兩組比較差異性顯著(P<0.05)。治療組無1例髮生心肌梗塞,對照組髮生1例(3%)。治療組無明顯不良反應。結論在雙聯抗血小闆治療基礎上加用低分子肝素鈉,能有效的控製不穩定型心絞痛(Ua)髮作,減少心肌梗塞的髮生。
목적:관찰저분자간소납병련용록필격뢰、배아사필림치료불은정형심교통(Ua)적림상료효。방법환자70례,남성57례,녀성13례,년령45~76(56.1±10.80)세。수궤분위대조조35례,급여록필격뢰、배아사필림구복。치료조35례,재대조조기출상가용저분자간소납(극새),매12소시피하주사,료정7천,관찰4주。결과치료조총유효솔97%,대조조총유효솔71.3%,량조비교차이성현저(P<0.05)。치료조무1례발생심기경새,대조조발생1례(3%)。치료조무명현불량반응。결론재쌍련항혈소판치료기출상가용저분자간소납,능유효적공제불은정형심교통(Ua)발작,감소심기경새적발생。
Objectiveto observe the low molecular heparin sodium in parallel with clopidogrel, aspirin in treatment of unstable angina pectoris (Ua) and the clinical curative effect.Methods 70 cases of patients, male 57 cases,female 13 cases, age 45 ~ 76 (56.1 ± 10.80) years old.Were randomly divided into 35 cases in the control group were given aspirin orally, Grey. t he treatment group of 35 cases, was treated with low molecular weight heparin(clexane), subcutaneously every 12 hours, 7 days, 4 weeks of observation.Results the total effective rate was 97% in treatment group, control group, the total efifciency of 71.3%, the difference between the two groups wassigniifcant (P < 0.05). the treatment group 1 cases withoutmyocardial infarction occurred in the control group, 1 cases(3%). the treatment group had no obvious adversereaction.Conclusion in the dual antiplatelet therapy combined with low molecular weight heparin sodium, can effectively control the unstable angina pe ctoris (Ua) attack,reduce the incidence of myocardial infarction.