中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
14期
32-34
,共3页
头孢哌酮舒巴坦%单纯性淋病%最佳剂量
頭孢哌酮舒巴坦%單純性淋病%最佳劑量
두포고동서파탄%단순성임병%최가제량
Cefoperazone sulbactam%Simple gonorrhea%Optimum dose
目的探讨头孢哌酮舒巴坦治疗单纯性淋病所需的最佳剂量。方法选取本院在2010年10月~2011年10月期间收治的单纯性淋病患者165例,电脑随机分成3组,即小剂量组55例,中剂量组55例,大剂量组55例,小剂量组给予头孢哌酮舒巴坦1.5 g/d,中剂量组给予头孢哌酮舒巴坦2.25 g/d,大剂量组给予头孢哌酮舒巴坦3 g/d,比较三组的临床效果和性价比情况。结果经分组治疗,小剂量组总有效率83.63%,中剂量组总有效率94.54%,大剂量组总有效率96.36%。可见中剂量组、大剂量组的临床治疗有效率明显优于小剂量组,差异有统计学意义(P<0.05)。中剂量组和大剂量组在临床治疗总有效率差异无统计学意义(P>0.05)；小剂量组药品合计花费20.10元,中剂量组药品合计花费30.15元,大<br> 剂量组药品合计花费40.20元,大剂量组的药品合计花费明显高于中剂量组。结论使用头孢哌酮舒巴坦治疗单纯性淋病所需的最佳剂量为2.25 g/d,其临床效果、性价比最为理想。
目的探討頭孢哌酮舒巴坦治療單純性淋病所需的最佳劑量。方法選取本院在2010年10月~2011年10月期間收治的單純性淋病患者165例,電腦隨機分成3組,即小劑量組55例,中劑量組55例,大劑量組55例,小劑量組給予頭孢哌酮舒巴坦1.5 g/d,中劑量組給予頭孢哌酮舒巴坦2.25 g/d,大劑量組給予頭孢哌酮舒巴坦3 g/d,比較三組的臨床效果和性價比情況。結果經分組治療,小劑量組總有效率83.63%,中劑量組總有效率94.54%,大劑量組總有效率96.36%。可見中劑量組、大劑量組的臨床治療有效率明顯優于小劑量組,差異有統計學意義(P<0.05)。中劑量組和大劑量組在臨床治療總有效率差異無統計學意義(P>0.05)；小劑量組藥品閤計花費20.10元,中劑量組藥品閤計花費30.15元,大<br> 劑量組藥品閤計花費40.20元,大劑量組的藥品閤計花費明顯高于中劑量組。結論使用頭孢哌酮舒巴坦治療單純性淋病所需的最佳劑量為2.25 g/d,其臨床效果、性價比最為理想。
목적탐토두포고동서파탄치료단순성임병소수적최가제량。방법선취본원재2010년10월~2011년10월기간수치적단순성임병환자165례,전뇌수궤분성3조,즉소제량조55례,중제량조55례,대제량조55례,소제량조급여두포고동서파탄1.5 g/d,중제량조급여두포고동서파탄2.25 g/d,대제량조급여두포고동서파탄3 g/d,비교삼조적림상효과화성개비정황。결과경분조치료,소제량조총유효솔83.63%,중제량조총유효솔94.54%,대제량조총유효솔96.36%。가견중제량조、대제량조적림상치료유효솔명현우우소제량조,차이유통계학의의(P<0.05)。중제량조화대제량조재림상치료총유효솔차이무통계학의의(P>0.05)；소제량조약품합계화비20.10원,중제량조약품합계화비30.15원,대<br> 제량조약품합계화비40.20원,대제량조적약품합계화비명현고우중제량조。결론사용두포고동서파탄치료단순성임병소수적최가제량위2.25 g/d,기림상효과、성개비최위이상。
Objective To investigate optimal dose for cefoperazone shubatan in the treatment of uncomplicated gonorrhea.Methods Selecting 165 cases of simple gonorrhea patients from October 2010 to October 2011 and randomly divided them into three groups, namely the small dose group 55 cases, 55 cases of middle dose group, high dose group 55 cases, small dose group was given in Shubatan daily 1.5 grams, middle dose group to cefoperazone Shubatan daily 2.25 grams, large dose group was given in Shubatan daily 3 grams, compared with three groups of clinical effectiveness and cost condition.Results After treatment with small dose group, the effective rate was 83.63%, the effective rate was 94.54% in dose, high dose rate was 96.36%. Visible middle dose group, high dose group clinical effective rate of the treatment group was significantly better than that of small dose, and there were significant differences,P<0.05. Middle dose group and high dose group in clinical effective rate of the treatment there was no significant difference,P>0.05; small dose drug together to spend 20.10 yuan, a dose of medicine total cost 30.15 yuan, large dose drug total cost 40.20 yuan, the total cost of the large dose group was significantly higher than that in drug dose group.Conclusion Optimal dose for cefoperazone shubatan in the treatment of uncomplicated gonorrhea is 2.25 grams per day, it has good clinical effectiveness and also the most cost-effective medicine.
