中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
16期
54-55
,共2页
HPV检测%人乳头瘤病毒%TCT细胞学检查%宫颈癌
HPV檢測%人乳頭瘤病毒%TCT細胞學檢查%宮頸癌
HPV검측%인유두류병독%TCT세포학검사%궁경암
HPV detection%Human papilloma virus%TCT cytology%Cervical cancer
目的:探讨高危型HPV检测联合细胞学检查在宫颈病变筛查中的的意义。方法:选取在笔者所在医院进行宫颈癌筛查检测的女性患者1875例,对所有患者分别进行高危型HPV基因检测(HR-HPV-DNA)、宫颈液基薄层细胞检测(TCT)、HR-HPV-DNA+TCT联合检查,以病理学检验为确诊依据。结果:在不同等级的宫颈病变中,HR-HPV+TCT检查的阳性率不同,宫颈癌前病变(CIN)Ⅰ级患者中为62.12%、CINⅡ患者中77.63%、CINⅢ患者中83.33%、宫颈浸润癌患者中92.31%,总敏感度为97.33%,特异度为71.20%。结论:高危型HPV检测联合细胞学检查应用于宫颈病变筛查中,可以增加筛查的有效率,适用于宫颈癌的早期诊断。
目的:探討高危型HPV檢測聯閤細胞學檢查在宮頸病變篩查中的的意義。方法:選取在筆者所在醫院進行宮頸癌篩查檢測的女性患者1875例,對所有患者分彆進行高危型HPV基因檢測(HR-HPV-DNA)、宮頸液基薄層細胞檢測(TCT)、HR-HPV-DNA+TCT聯閤檢查,以病理學檢驗為確診依據。結果:在不同等級的宮頸病變中,HR-HPV+TCT檢查的暘性率不同,宮頸癌前病變(CIN)Ⅰ級患者中為62.12%、CINⅡ患者中77.63%、CINⅢ患者中83.33%、宮頸浸潤癌患者中92.31%,總敏感度為97.33%,特異度為71.20%。結論:高危型HPV檢測聯閤細胞學檢查應用于宮頸病變篩查中,可以增加篩查的有效率,適用于宮頸癌的早期診斷。
목적:탐토고위형HPV검측연합세포학검사재궁경병변사사중적적의의。방법:선취재필자소재의원진행궁경암사사검측적녀성환자1875례,대소유환자분별진행고위형HPV기인검측(HR-HPV-DNA)、궁경액기박층세포검측(TCT)、HR-HPV-DNA+TCT연합검사,이병이학검험위학진의거。결과:재불동등급적궁경병변중,HR-HPV+TCT검사적양성솔불동,궁경암전병변(CIN)Ⅰ급환자중위62.12%、CINⅡ환자중77.63%、CINⅢ환자중83.33%、궁경침윤암환자중92.31%,총민감도위97.33%,특이도위71.20%。결론:고위형HPV검측연합세포학검사응용우궁경병변사사중,가이증가사사적유효솔,괄용우궁경암적조기진단。
Objective:To investigate the significance of the detection of high-risk HPV combined with cytological examination in cervical lesions screening. Method:1875 cases of female patients,screening for cervical cancer.All of the patients,respectively for HPV type gene detection(HR HPV-DNA),cervical liquid thin layer cell test(TCT),HR-HPV DNA+TCT joint inspection,pathological diagnosis standard for inspection.Result:In different levels of cervical lesions, HR-check out the positive rate of HPV+TCT was different.CIN Ⅰ patients was 62.12%,CIN Ⅱ patients was 77.63%,CIN Ⅲpatients was 83.33%,92.31%of patients with cervical invasive cancer.The overall sensitivity was 97.33%.Specific degree was 71.20%.Conclusion:High-risk type HPV detection combined cytological examination,used in screening of cervical lesions,can increase the screening efficiency,is suitable for early diagnosis of cervical cancer.