医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
16期
635-635
,共1页
甲硝唑%饮酒%双硫仑反应
甲硝唑%飲酒%雙硫崙反應
갑초서%음주%쌍류륜반응
Metronidazole%Drinking%Disulfiram reaction
目的：加强应对因甲硝唑治愈急性智齿冠周炎后饮酒造成双硫仑样反应的应对及具体措施。方法给予吸氧，异丙嗪25mg肌内注射，5%葡萄糖1000ml＋维生素C 200mg＋维生素B6200mg＋10%氯化钾10ml静脉滴注。结果静脉滴注用药3h后头痛、头晕、心悸、胸闷、气短、烦躁，呕吐症状基本消失。结论双硫仑样反应多数是在患者用药期间或停药后5~7d内饮酒诱发，对患者及其家属要明确告知在应用相关药物期间及停药后10d内禁止饮酒及含酒饮品，以免引起不良反应甚至严重后果。
目的：加彊應對因甲硝唑治愈急性智齒冠週炎後飲酒造成雙硫崙樣反應的應對及具體措施。方法給予吸氧，異丙嗪25mg肌內註射，5%葡萄糖1000ml＋維生素C 200mg＋維生素B6200mg＋10%氯化鉀10ml靜脈滴註。結果靜脈滴註用藥3h後頭痛、頭暈、心悸、胸悶、氣短、煩躁，嘔吐癥狀基本消失。結論雙硫崙樣反應多數是在患者用藥期間或停藥後5~7d內飲酒誘髮，對患者及其傢屬要明確告知在應用相關藥物期間及停藥後10d內禁止飲酒及含酒飲品，以免引起不良反應甚至嚴重後果。
목적：가강응대인갑초서치유급성지치관주염후음주조성쌍류륜양반응적응대급구체조시。방법급여흡양，이병진25mg기내주사，5%포도당1000ml＋유생소C 200mg＋유생소B6200mg＋10%록화갑10ml정맥적주。결과정맥적주용약3h후두통、두훈、심계、흉민、기단、번조，구토증상기본소실。결론쌍류륜양반응다수시재환자용약기간혹정약후5~7d내음주유발，대환자급기가속요명학고지재응용상관약물기간급정약후10d내금지음주급함주음품，이면인기불량반응심지엄중후과。
Objective To strengthen the response due to metronidazole cure acute pericoronitis and specific measures to deal with alcohol cause disulfiram-like reaction. Methods Given oxygen, promethazine 25mg intramuscular injection, 5% dextrose 1000ml + Vitamin C 200mg + Vitamin B6 200mg +10% potassium chloride 10ml intravenously. Results After intravenous administration three hours of headache, dizziness, palpitations, chest tightness, shortness of breath, irritability, vomiting symptoms disappeared. Conclusion Disulfiram-like reaction during most of the patients after discontinuation of medication or alcohol-induced 5-7 days, severe clinical manifestations, and easily misdiagnosed. For patients and their families to clearly inform the application within 10 days after the period of withdrawal-related drugs and alcohol and alcoholic beverages is prohibited in order to avoid adverse reactions or serious consequences.
