CAJ | 학술논문

目的：分析新鲜冰冻血浆(FFP)的不合理输注原因，减少FFP不合理输注。方法回顾性分析深圳市龙岗区坪地人民医院493例输注FFP的病历资料，输注目的；比较合理输注组和不合理输注组在输注FFP前及输注后8 h内凝血酶原时间(PT)及活化部分凝血活酶时间(APTT)的检查结果。结果输注FFP患者中，合理输注者为63.61%(314/439)，不合理输注者为36.31%(179/439)；合理组PT、APTT值输注后明显低于输注前，差异有统计学意义(P<0.05)，不合理组输注前、后PT、APTT值比较，两者差异无统计学意义。结论以补充蛋白、扩容及增加营养者为目的是导致FFP输注不合理的最主要原因。非大量出血或凝血功能异常者即使输注FFP也不会改善凝血功能。为促进临床输血安全性的提升，节约有限的血液资源，需要临床上加强FFP的输血管理。
목적：분석신선빙동혈장(FFP)적불합리수주원인，감소FFP불합리수주。방법회고성분석심수시룡강구평지인민의원493례수주FFP적병력자료，수주목적；비교합리수주조화불합리수주조재수주FFP전급수주후8 h내응혈매원시간(PT)급활화부분응혈활매시간(APTT)적검사결과。결과수주FFP환자중，합리수주자위63.61%(314/439)，불합리수주자위36.31%(179/439)；합리조PT、APTT치수주후명현저우수주전，차이유통계학의의(P<0.05)，불합리조수주전、후PT、APTT치비교，량자차이무통계학의의。결론이보충단백、확용급증가영양자위목적시도치FFP수주불합리적최주요원인。비대량출혈혹응혈공능이상자즉사수주FFP야불회개선응혈공능。위촉진림상수혈안전성적제승，절약유한적혈액자원，수요림상상가강FFP적수혈관리。
Objective Analysis of the infusion of fresh frozen plasma (FFP) unreasonable reason, reduce the unreasonable FFP infusion. Methods Longgang district of shenzhen ping to people's hospital were retrospectively analyzed in 493 cases of medical records of infusion FFP, infusion purposes;Infusion of reasonable and unreasonable infusion group within the infusion infusion of FFP before and after 8 h prothrombin time (PT) and activated partial blood clotting enzyme time (APTT) test results. Results The ratio of reasonable FFP transfusion was 63.61%(314/439), and the ratio of unreasonable FFP transfusion was 36.31%(179/439). The result had statistical significance which PT and APTT between before blood transfusion and 8 h after blood transfusion in reasonable FFP transfusion (P<0.05). The result had no statistical significance which PT and APTT between before blood transfusion and 8 h after blood transfusion in unreasonable FFP transfusion. Conclusion To supplement protein, expansion and increase nutrition for purpose is the main cause of the FFP infusion is not reasonable. Not a lot of bleeding or clotting function was abnormal and even infusion FFP can not improve the function of blood coagulation. In order to promote the ascension of clinical blood transfusion safety, save the limited resources of blood, the need to strengthen the clinical transfusion management of FFP.