当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
16期
1-2
,共2页
布托啡诺%甲磺酸罗哌卡因%硬膜外自控镇痛%中期妊娠引产
佈託啡諾%甲磺痠囉哌卡因%硬膜外自控鎮痛%中期妊娠引產
포탁배낙%갑광산라고잡인%경막외자공진통%중기임신인산
Butorphanol%Ropivacaine mesilate%Patient controlled epidural analgesia(PECA)%Mid-term pregnancy induced labor
目的：将不同剂量布托啡诺复合甲磺酸罗哌卡因应用于中期妊娠引产硬膜外镇痛效果评价，探讨其最佳剂量。方法150例(ASA I～Ⅱ级)中孕产妇随机均分为5组（n=30），即吗啡组(M组)布托啡诺组(B 1、B 2、B 3、B 4组)。记录患者不同时点VAS评分、Ramsay评分、BCS评分及不良反应。结果（1）B 1组VAS评分分别在镇痛后10、30、90 min高于M组，B 2、B 3、B 4组与M组无明显差异；B 1组BCS评分在镇痛后10、30、90 min及清宫时低于M组，B 2、B 3、B 4组与M组无明显差异。（2）不良反应：M组恶心呕吐、皮肤瘙痒发生率高于B 1、B 2、B 3、B 4组，且差异显著。B 3，B 4组嗜睡发生率高。结论0.004%及以上浓度的布托啡诺复合甲磺酸罗哌卡因应用于中期妊娠引产的硬膜外镇痛效果确切、不良反应少，因而具有良好的临床应用价值。
目的：將不同劑量佈託啡諾複閤甲磺痠囉哌卡因應用于中期妊娠引產硬膜外鎮痛效果評價，探討其最佳劑量。方法150例(ASA I～Ⅱ級)中孕產婦隨機均分為5組（n=30），即嗎啡組(M組)佈託啡諾組(B 1、B 2、B 3、B 4組)。記錄患者不同時點VAS評分、Ramsay評分、BCS評分及不良反應。結果（1）B 1組VAS評分分彆在鎮痛後10、30、90 min高于M組，B 2、B 3、B 4組與M組無明顯差異；B 1組BCS評分在鎮痛後10、30、90 min及清宮時低于M組，B 2、B 3、B 4組與M組無明顯差異。（2）不良反應：M組噁心嘔吐、皮膚瘙癢髮生率高于B 1、B 2、B 3、B 4組，且差異顯著。B 3，B 4組嗜睡髮生率高。結論0.004%及以上濃度的佈託啡諾複閤甲磺痠囉哌卡因應用于中期妊娠引產的硬膜外鎮痛效果確切、不良反應少，因而具有良好的臨床應用價值。
목적：장불동제량포탁배낙복합갑광산라고잡인응용우중기임신인산경막외진통효과평개，탐토기최가제량。방법150례(ASA I～Ⅱ급)중잉산부수궤균분위5조（n=30），즉마배조(M조)포탁배낙조(B 1、B 2、B 3、B 4조)。기록환자불동시점VAS평분、Ramsay평분、BCS평분급불량반응。결과（1）B 1조VAS평분분별재진통후10、30、90 min고우M조，B 2、B 3、B 4조여M조무명현차이；B 1조BCS평분재진통후10、30、90 min급청궁시저우M조，B 2、B 3、B 4조여M조무명현차이。（2）불량반응：M조악심구토、피부소양발생솔고우B 1、B 2、B 3、B 4조，차차이현저。B 3，B 4조기수발생솔고。결론0.004%급이상농도적포탁배낙복합갑광산라고잡인응용우중기임신인산적경막외진통효과학절、불량반응소，인이구유량호적림상응용개치。
Objective To study the different doses butorphanol combined with Ropivacaine mesylate applied in mid pregnancy induced labor epidural analgesia effect comparison, and discuss the best dose of it. Methods 150 cases (ASAⅠorⅡ) mid-term pregnancy induced labor maternal randomly were divided into 5 groups,30 cases in one group, control group (Group M),the experimental group (Group B 1,B 2,B 3,B 4) and PECA (Patient controlled epidural analgesia):recorded the scores of VAS grade,Ramsay,BCS and adverse reactions in two groups at different times. Results(1)VAS in Group B 1 was higher than that in Group M at 10’, 30’and 90’during analgesia. While it showed no difference between Group B 2、Group B 3、Group B 4 and Group M;BCS in Group B 1 was lower than that in Group M at 10’,30’and 90’during analgesia and curettage of uterine cavity,while it showeed no difference between Group B 2、Group B 3,Group B 4 and GroupM;(2)The incidence of complications such as nausea,vomiting and itch of skin in Group M was higher than that in Group B 1,Group B 2,Group B 3 and Group 4, and the difference was significant. Conclusion Applied in mid pregnancy induced labor epidural analgesia, 0.004%butorphanol composite Ropivacaine mesylate effect exact and hasless complication. Therefore this method has an excellent clinical.
