CAJ | 학술논문

目的：探讨婴幼儿维生素D缺乏性佝偻病的防治方法，即在服用维生素D3400IU基础上，是否需同时添加钙剂。方法：将120例足月出生的健康婴儿随机分为观察组(单纯添加维生素D3)和对照组(添加维生素D3和钙剂)，随访两组婴儿至6个月，观察其生长发育情况、佝偻病患病情况以及6个月时血清25-羟维生素D[25-(OH)D]及血钙水平。结果：两组婴儿在发育指标、佝偻病患病率、血清25-(OH)D及血钙水平上的差异均无统计学意义(P＞0.05)。结论：对于足月出生的健康新生儿，在婴儿期只要保证摄入维生素D3400IU，即能达到预防佝偻病的目的，无需额外补充钙剂。
목적：탐토영유인유생소D결핍성구루병적방치방법，즉재복용유생소D3400IU기출상，시부수동시첨가개제。방법：장120례족월출생적건강영인수궤분위관찰조(단순첨가유생소D3)화대조조(첨가유생소D3화개제)，수방량조영인지6개월，관찰기생장발육정황、구루병환병정황이급6개월시혈청25-간유생소D[25-(OH)D]급혈개수평。결과：량조영인재발육지표、구루병환병솔、혈청25-(OH)D급혈개수평상적차이균무통계학의의(P＞0.05)。결론：대우족월출생적건강신생인，재영인기지요보증섭입유생소D3400IU，즉능체도예방구루병적목적，무수액외보충개제。
Objective:To investigate the prevention and treatment methods for the infants with vitamin D deficiency rickets, whether to add calcium when took Vitamin D3 400IU.Methods:120 healthy infants born at term were randomly divided into the observation group(simple add Vitamin D3) and the control group(add Vitamin D3 and calcium).We followed them for 6 months to observe the growth and development situation,the prevalence of rickets and the serum 25-hydroxyvitamin D[25-(OH)D] and serum calcium levels at 6 months. Results: There were no significant differences in the development index,the prevalence of rickets,the 25-(OH)D and serum calcium levels of the two groups (P>0.05).Conclusion:For the full-term born healthy neonates,if we guarantee the intake of Vitamin D3 400IU in infancy,which can reach the purpose of preventing rickets,so we need not add the calcium.