中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
17期
14-16
,共3页
急性脑梗死%银杏达莫%奥扎格雷钠
急性腦梗死%銀杏達莫%奧扎格雷鈉
급성뇌경사%은행체막%오찰격뢰납
Acute cerebral infarction%Ginkgo-damole%Sodium ozagrel
目的：探讨银杏达莫联合奥扎格雷钠治疗急性脑梗死的疗效。方法：2012年1-12月收治急性脑卒中患者120例。将所有患者随机分为两组，每组80例，Ⅰ组给予奥扎格雷钠80mg静滴治疗，1次/日。Ⅱ组给予奥扎格雷钠80mg联合银杏达莫20ml静滴治疗，2次/日。同时，所有患者给予阿司匹林200mg口服，抗血小板聚集，依达拉奉注射液20ml静滴脑保护治疗。结果：①两组患者治疗后与治疗前对比NIHSS评分均有降低(P＜0.05)，两组患者治疗后NIHSS 评分Ⅱ组比Ⅰ组下降更加明显，两者对比差异有统计学意义(P＜0.05)。其中Ⅰ组患者发生进展23例(38.3%)，Ⅱ组患者发生进展13例(21.7%)。两组患者发生进展所占比例对比差异有统计学意义(P＜0.05)。②两组患者治疗后临床疗效的评定比较：两组患者治疗后总有效率分别为75%和90%，可见Ⅱ组优于Ⅰ组，两组对比差异有统计学意义(P＜0.05)。结论：通过临床观察，奥扎格雷钠联合与银杏达莫联合应用有协同作用，其治疗急性脑梗死在临床疗效、促进神经功能恢复、阻止卒中进展等方面疗效显著，值得进一步研究和推广。
目的：探討銀杏達莫聯閤奧扎格雷鈉治療急性腦梗死的療效。方法：2012年1-12月收治急性腦卒中患者120例。將所有患者隨機分為兩組，每組80例，Ⅰ組給予奧扎格雷鈉80mg靜滴治療，1次/日。Ⅱ組給予奧扎格雷鈉80mg聯閤銀杏達莫20ml靜滴治療，2次/日。同時，所有患者給予阿司匹林200mg口服，抗血小闆聚集，依達拉奉註射液20ml靜滴腦保護治療。結果：①兩組患者治療後與治療前對比NIHSS評分均有降低(P＜0.05)，兩組患者治療後NIHSS 評分Ⅱ組比Ⅰ組下降更加明顯，兩者對比差異有統計學意義(P＜0.05)。其中Ⅰ組患者髮生進展23例(38.3%)，Ⅱ組患者髮生進展13例(21.7%)。兩組患者髮生進展所佔比例對比差異有統計學意義(P＜0.05)。②兩組患者治療後臨床療效的評定比較：兩組患者治療後總有效率分彆為75%和90%，可見Ⅱ組優于Ⅰ組，兩組對比差異有統計學意義(P＜0.05)。結論：通過臨床觀察，奧扎格雷鈉聯閤與銀杏達莫聯閤應用有協同作用，其治療急性腦梗死在臨床療效、促進神經功能恢複、阻止卒中進展等方麵療效顯著，值得進一步研究和推廣。
목적：탐토은행체막연합오찰격뢰납치료급성뇌경사적료효。방법：2012년1-12월수치급성뇌졸중환자120례。장소유환자수궤분위량조，매조80례，Ⅰ조급여오찰격뢰납80mg정적치료，1차/일。Ⅱ조급여오찰격뢰납80mg연합은행체막20ml정적치료，2차/일。동시，소유환자급여아사필림200mg구복，항혈소판취집，의체랍봉주사액20ml정적뇌보호치료。결과：①량조환자치료후여치료전대비NIHSS평분균유강저(P＜0.05)，량조환자치료후NIHSS 평분Ⅱ조비Ⅰ조하강경가명현，량자대비차이유통계학의의(P＜0.05)。기중Ⅰ조환자발생진전23례(38.3%)，Ⅱ조환자발생진전13례(21.7%)。량조환자발생진전소점비례대비차이유통계학의의(P＜0.05)。②량조환자치료후림상료효적평정비교：량조환자치료후총유효솔분별위75%화90%，가견Ⅱ조우우Ⅰ조，량조대비차이유통계학의의(P＜0.05)。결론：통과림상관찰，오찰격뢰납연합여은행체막연합응용유협동작용，기치료급성뇌경사재림상료효、촉진신경공능회복、조지졸중진전등방면료효현저，치득진일보연구화추엄。
Objective:To expolore the curative effect of ginkgo-damole combined with sodium ozagrel in the treatment of acute cerebral infarction.Methods:120 cases with acute stroke were selected from January to December 2012.All cases were randomly divided into two groups with 80 cases in each.Ⅰ group were given with 80mg sodium ozagrel intravenous drip treatment,1 time one day.Ⅱ group were given with 80mg sodium ozagrel combined with 20ml ginkgo-damole intravenous drip treatment,2 times one day.All cases were given 200mg aspirin oral,anti platelet aggregation,20ml edaravone injection intravenous infusion for cerebral protection.Results:①Compared with before treatment,the NIHSS grades of patiens of the two groups after treatment were decreased(P<0.05).After treatment,the the NIHSS grade of Ⅱ group was more significantly decreased than that of Ⅰ group.The difference was statistically significant(P<0.05).The number of occurrence progress in Ⅰ group was 23(38.3%).The number of occurrence progress in Ⅱ group was 13(21.7%).The proportion of the number of occurrence progress in the two groups were compared.The difference was statistically significant(P<0.05).②The evaluations of clinical curative effect of the two groups after treatment were compared.The total effective rates of the two groups after treatment were respectively 75% and 90%.It can visible that Ⅱ group was better than Ⅰ group.There was statistical significance between the two groups(P<0.05).Conclusion:Through clinical observation,the application of ginkgo-damole combined with sodium ozagrel has synergistic function.It has significant effect on clinical effect,promoting the recovery of neurological function,preventing the progress of stroke.It is worthy of further research and extension.
