CAJ | 학술논문

目的：探讨冠状动脉慢血流(SCF)与血浆内皮素水平(ET)的相关分析。方法：2012年8月-2014年2月收治行冠状动脉造影(CAG)提示心外膜主要冠状动脉无明显病变患者84例。采用校正TIMI血流计帧法(cTFC)，将冠状动脉平均帧数＞27帧者归为SCF，将患者分为SCF组(36例)和对照组(48例)。应用t检验和卡方检验对两组临床资料进行比较，并通过logistic回归分析对ET水平进行分析。结果：两组患者性别、BMI、高血压、糖尿病、高脂血症、吸烟史比例、血红蛋白、血小板、白细胞计数、空腹血糖、甘油三酯及总胆固醇差异无统计学意义，而SCF组ET水平显著高于对照组。Logistic回归分析表明ET是SCF的危险因素。结论：ET水平与SCF有关，可能参与了SCF病理生理过程。
목적：탐토관상동맥만혈류(SCF)여혈장내피소수평(ET)적상관분석。방법：2012년8월-2014년2월수치행관상동맥조영(CAG)제시심외막주요관상동맥무명현병변환자84례。채용교정TIMI혈류계정법(cTFC)，장관상동맥평균정수＞27정자귀위SCF，장환자분위SCF조(36례)화대조조(48례)。응용t검험화잡방검험대량조림상자료진행비교，병통과logistic회귀분석대ET수평진행분석。결과：량조환자성별、BMI、고혈압、당뇨병、고지혈증、흡연사비례、혈홍단백、혈소판、백세포계수、공복혈당、감유삼지급총담고순차이무통계학의의，이SCF조ET수평현저고우대조조。Logistic회귀분석표명ET시SCF적위험인소。결론：ET수평여SCF유관，가능삼여료SCF병리생리과정。
Objective:To explore the correlation analysis of coronary slow flow phenomenon and plasma endothelin.Methods:The coronary arteriography(CAG) of 84 cases prompted epicardial main coronary arteries with no obvious pathological changes.The 84 cases were selected from August 2012 to February 2014.Using the corrected TIMI frame count(cTFC) of blood flow,the average frame of coronary artery were more than 27 frames as SCF.The cases were divided into SCF group with 36 cases and the control group with 48 cases.The clinical data of the two groups were compared by using t test and chi square test.The ET level was analyzed by logistic regression analysis.Results:The difference of gender,BMI,hypertension,diabetes,hyperlipemia,the roportion of smoking history,hemoglobin,platelet,white blood cell count,fasting blood glucose,triglyceride and total cholesterol of the two groups were no statistical significance.The ET level of SCF group was significantly higher than that of the control group.Logistic regression analysis showed that ET was a risk factor for SCF.Conclusion:The ET level has a relation with SCF.It may be involved in the pathophysiological process of SCF.