CAJ | 학술논문

目的：探讨脂蛋白a [Lp(a)]与急性ST段抬高型心肌梗死(STEMI)患者梗死相关动脉(IRA)自发再通(SR)的相关性。方法连续观察118例直接行急诊经皮冠状动脉介入治疗的STEMI患者，根据梗死相关动脉造影结果分为自发再通组(前向血流TIMI 2～3级,n=26)和闭塞组(前向血流 TIM10～1级,n=92)，所有病例均采取静脉血5 mL，进行血生化检查，从中获得血清Lp(a)数值，然后将所得结果进行统计学分析。结果闭塞组 Lp(a)水平明显高于自发再通组（237±150）mg/L VS 148±96）mg/L，差异有统计学意义(P<0.01)。结论血清Lp(a)水平可以作为STEMI患者梗死相关动脉(IRA)早期自发再通的一个预测指标。
목적：탐토지단백a [Lp(a)]여급성ST단태고형심기경사(STEMI)환자경사상관동맥(IRA)자발재통(SR)적상관성。방법련속관찰118례직접행급진경피관상동맥개입치료적STEMI환자，근거경사상관동맥조영결과분위자발재통조(전향혈류TIMI 2～3급,n=26)화폐새조(전향혈류 TIM10～1급,n=92)，소유병례균채취정맥혈5 mL，진행혈생화검사，종중획득혈청Lp(a)수치，연후장소득결과진행통계학분석。결과폐새조 Lp(a)수평명현고우자발재통조（237±150）mg/L VS 148±96）mg/L，차이유통계학의의(P<0.01)。결론혈청Lp(a)수평가이작위STEMI환자경사상관동맥(IRA)조기자발재통적일개예측지표。
0bjective To explore the relationship between spontaneous recanalization of infarct-related arteries in patients with ST-segment elevation myocardial infarction (STEMI) and plasma level of lipoprotein Lp (a). Methods A total of 118 patients with STEMI whose blood were obtained at the admission and Lp (a) was measured. Subjects were divided into 2 groups according to the thrombolysis in myocardial infaction (TIMI) grade, Spontaneous recanalization(SR)group(TIMI 2-3, n = 26) versus Persistent occlusion group (TIMI 0-1, n = 92). Results The Lp(a) level was higher in Persistent occlusion group than in SR group(237±150mg/L VS 148±96 mg/L)(P<0.01). Conclusion Plasma level of Lp(a) appeared to be a predictor for patients with spontaneous recanalization of infarct-related arteries in the early phase of STEMI.