临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2014年
17期
16-20
,共5页
徐国宏%李德福%邓先锐%岳文杰%胥钱平
徐國宏%李德福%鄧先銳%嶽文傑%胥錢平
서국굉%리덕복%산선예%악문걸%서전평
直肠癌%TNE%腹腔镜%成本-效益分析
直腸癌%TNE%腹腔鏡%成本-效益分析
직장암%TNE%복강경%성본-효익분석
Rectal cancer%TNE%Laparoscope%Cost-effectiveness analysis
目的:比较直肠癌腹腔镜下TNE术与传统开腹TNE术围手术期相关指标及病理数据,分析2种术式特点及术后短期效果差异。方法对76例行腹腔镜下TNE术的直肠癌患者与62例行开腹TNE术直肠癌患者进行回顾性队列研究的资料采集,采集包括手术时间、麻醉时间、失血量、术中输血、手术切口长度、切口感染、其他并发症、术后住院时间及院内病死率在内的反映手术短期效果的数据,同时采集反映肿瘤大小、检获淋巴结数目、肿瘤距远端或近端切缘的距离以及切缘肿瘤阳性率在内的组织病理学数据;采用回顾性队列研究的研究方法,统计分析2种术式在上述各个方面的数据特点,探讨两者在围手术期各个具体指标上的差异性。结果开腹组在手术时间、麻醉时间等项目上较腹腔镜组而言并不具有明显的优势;而腹腔镜组在术后恢复指标上,如术后镇痛药使用、术后肛门恢复排气时间、术后恢复进食时间及术后住院时间等方面,占有明显的优势,且这样的优势具有统计学意义。结论腹腔镜TNE术式在术后镇痛药使用、胃肠功能恢复及住院时间等指标上较传统开腹术式仍具有优势。
目的:比較直腸癌腹腔鏡下TNE術與傳統開腹TNE術圍手術期相關指標及病理數據,分析2種術式特點及術後短期效果差異。方法對76例行腹腔鏡下TNE術的直腸癌患者與62例行開腹TNE術直腸癌患者進行迴顧性隊列研究的資料採集,採集包括手術時間、痳醉時間、失血量、術中輸血、手術切口長度、切口感染、其他併髮癥、術後住院時間及院內病死率在內的反映手術短期效果的數據,同時採集反映腫瘤大小、檢穫淋巴結數目、腫瘤距遠耑或近耑切緣的距離以及切緣腫瘤暘性率在內的組織病理學數據;採用迴顧性隊列研究的研究方法,統計分析2種術式在上述各箇方麵的數據特點,探討兩者在圍手術期各箇具體指標上的差異性。結果開腹組在手術時間、痳醉時間等項目上較腹腔鏡組而言併不具有明顯的優勢;而腹腔鏡組在術後恢複指標上,如術後鎮痛藥使用、術後肛門恢複排氣時間、術後恢複進食時間及術後住院時間等方麵,佔有明顯的優勢,且這樣的優勢具有統計學意義。結論腹腔鏡TNE術式在術後鎮痛藥使用、胃腸功能恢複及住院時間等指標上較傳統開腹術式仍具有優勢。
목적:비교직장암복강경하TNE술여전통개복TNE술위수술기상관지표급병리수거,분석2충술식특점급술후단기효과차이。방법대76례행복강경하TNE술적직장암환자여62례행개복TNE술직장암환자진행회고성대렬연구적자료채집,채집포괄수술시간、마취시간、실혈량、술중수혈、수술절구장도、절구감염、기타병발증、술후주원시간급원내병사솔재내적반영수술단기효과적수거,동시채집반영종류대소、검획림파결수목、종류거원단혹근단절연적거리이급절연종류양성솔재내적조직병이학수거;채용회고성대렬연구적연구방법,통계분석2충술식재상술각개방면적수거특점,탐토량자재위수술기각개구체지표상적차이성。결과개복조재수술시간、마취시간등항목상교복강경조이언병불구유명현적우세;이복강경조재술후회복지표상,여술후진통약사용、술후항문회복배기시간、술후회복진식시간급술후주원시간등방면,점유명현적우세,차저양적우세구유통계학의의。결론복강경TNE술식재술후진통약사용、위장공능회복급주원시간등지표상교전통개복술식잉구유우세。
Objective To analyse the different characteristics and short-term effect by comparing peri-operative relat-ed index and pathological data between laparoscopic and traditional open TNE rectomy. Methods 76 cases of patients under-went laparoscopic TNE rectomy and 62 of patients underwent open TNE rectomy were enrolled as treatment group and control group respectively,and retrospective cohort study was applied to analyze. Following indexes were collected:to reflect the effect of short-term operation data such as length of surgery,length of anesthesia,loss of blood,intro-operation transfusion,length of incision wound,incision infection,other complication,hospitalization time after operation and fatality rate in hospital;and pathohistologic data were collected including in tumor size,number of lymph nodes,the distance from the distal or proximal re-section margin of the tumor and positive rate of resection margin. Retrospective cohort study was adopted to analyse the charac-teristics of collected data in each aspects mentioned above respectively,and differences of peri-operation indexes were dis-cussed. Results Compared to the traditional open group,the laparoscopic group had no significant advantages in the length of surgery and anesthesia,while the laparoscopic group had significant advantages in post-operative recovery index,including less use of analgesic,earlier recovery of fart and diet and shorter length of post-operative stay,which was statistically significant. Conclusion Laparoscopic TNE has advantages in post-operative analgesic adoption,recovery of gastrointestinal function and post-operative stay Compared to the traditional open surgery.