CAJ | 학술논문

目的：利用磁敏感加权成像（ SWI ）检测脑内微出血，并探讨脑出血、脑内微出血与脑血管病危险因素之间的关系。方法回顾性分析从2012年8月至2013年6月于温州医科大学附属第二医院进行了SWI检查的患者共70例，其中男42例、女28例，年龄30～88（68±14）岁。总结患者的性别、年龄、高血压、糖尿病、高血脂情况。由一名具有10年以上MRI经验的主任医师对常规MRI影像及SWI图像进行分析，记录脑梗死、陈旧出血的发生情况及脑微出血的个数。然后运用SPSS 13.0对资料进行统计分析，以脑出血为因变量，以脑内微出血、脑血管的高危因素为自变量做二元逻辑回归分析；以脑内微出血的数量为因变量，以性别、年龄、脑出血、脑血管的高危因素为自变量做线性回归分析。按P＜0.05为差异有统计学意义。结果脑内微出血的个数为0～65个；44例发生过梗死，7例发生过陈旧出血；经二元逻辑回归分析发现脑内出血与高脂血症有相关性（P ＝0.017）；经线性回归分析发现脑微出血与脑出血有相关性（P＝0.023）。结论 SWI评价脑内微出血有助于评估脑血管病患者脑出血发生的可能性，为临床治疗及采取相应预防措施提供依据。
목적：이용자민감가권성상（ SWI ）검측뇌내미출혈，병탐토뇌출혈、뇌내미출혈여뇌혈관병위험인소지간적관계。방법회고성분석종2012년8월지2013년6월우온주의과대학부속제이의원진행료SWI검사적환자공70례，기중남42례、녀28례，년령30～88（68±14）세。총결환자적성별、년령、고혈압、당뇨병、고혈지정황。유일명구유10년이상MRI경험적주임의사대상규MRI영상급SWI도상진행분석，기록뇌경사、진구출혈적발생정황급뇌미출혈적개수。연후운용SPSS 13.0대자료진행통계분석，이뇌출혈위인변량，이뇌내미출혈、뇌혈관적고위인소위자변량주이원라집회귀분석；이뇌내미출혈적수량위인변량，이성별、년령、뇌출혈、뇌혈관적고위인소위자변량주선성회귀분석。안P＜0.05위차이유통계학의의。결과뇌내미출혈적개수위0～65개；44례발생과경사，7례발생과진구출혈；경이원라집회귀분석발현뇌내출혈여고지혈증유상관성（P ＝0.017）；경선성회귀분석발현뇌미출혈여뇌출혈유상관성（P＝0.023）。결론 SWI평개뇌내미출혈유조우평고뇌혈관병환자뇌출혈발생적가능성，위림상치료급채취상응예방조시제공의거。
Objective To detect cerebral microbleeds by susceptibility weighted imaging and explore the relationship between intracerebral hemorrhage , cerebral microbleeds and risk factors of cerebral vascular disease.Methods A retrospective analysis was conducted for 70 patients from August 2012 to June 2013 undergoing susceptibility weighted imaging ( SWI ).The average age was ( 68 ±14 ) years.Their demographic and clinical profiles were recorded.Conventional magnetic resonance imaging ( MRI) and SWI images were performed and images analyzed by an experienced radiologist.The occurrence of infarction , hemorrhage and number of microbleeds were recorded.Then regression analysis with SPSS 13.0 was used to define the relationship between the existence of infarction , hemorrhage and the number of microbleeds.Results There were 0-65 microbleeds in brains on SWI.There were infarction (n=44) and chronic intracranial hemorrhage ( n =7 ).The binary Logistic regression analysis showed that intracranial hemorrhage was associated with hyperlipidemia ( P =0.01 ).Linear regression analysis showed that the number of microbleeds was related with intracranial hemorrhage ( P=0.02 ).Conclusion Evaluation of microbleeds in brain by SWI may help to assess the possibility of intracranial hemorrhage so as to provides rationales for clinical therapeutics.