中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
15期
5-7
,共3页
腹膜透析%腹膜炎%致病菌%耐药性
腹膜透析%腹膜炎%緻病菌%耐藥性
복막투석%복막염%치병균%내약성
Peritoneal dialysis%Peritonitis%Pathogenic bacteria%Drug resistance
目的：探讨腹膜透析相关性腹膜炎的致病菌及细菌耐药情况，指导临床用药。方法回顾性分析该腹膜透析中心2009年12月-2013年8月共70例腹膜炎患者的腹膜透析流出液培养+药敏结果。其中男性50例，女性20例，年龄21～77岁，平均（46.8±26.3）岁。结果其中复发3例，再发1例，药敏培养阳性23例，阳性率为38.3%，其中革兰氏阳性菌占10例（43.5%），革兰氏阴性菌12例（52.2%），真菌1例（4.3%）；革兰阳性球菌对万古霉素均敏感，对青霉素耐药率较高（80%），苯唑西林耐药率83.3%，红霉素耐药率100%；革兰阴性菌对美洛培南、亚胺培南、丁胺卡那霉素、哌拉西林他唑巴坦均敏感，头孢他啶敏感率较高（90%），氨苄西林均耐药。结论革兰氏阳性菌和阴性菌所占比例相当，对氨苄西林均耐药。革兰氏阳性球菌对万古霉素敏感，革兰氏阴性菌对美洛培南、亚胺培南、丁胺卡那霉素、哌拉西林他唑巴坦敏感。
目的：探討腹膜透析相關性腹膜炎的緻病菌及細菌耐藥情況，指導臨床用藥。方法迴顧性分析該腹膜透析中心2009年12月-2013年8月共70例腹膜炎患者的腹膜透析流齣液培養+藥敏結果。其中男性50例，女性20例，年齡21～77歲，平均（46.8±26.3）歲。結果其中複髮3例，再髮1例，藥敏培養暘性23例，暘性率為38.3%，其中革蘭氏暘性菌佔10例（43.5%），革蘭氏陰性菌12例（52.2%），真菌1例（4.3%）；革蘭暘性毬菌對萬古黴素均敏感，對青黴素耐藥率較高（80%），苯唑西林耐藥率83.3%，紅黴素耐藥率100%；革蘭陰性菌對美洛培南、亞胺培南、丁胺卡那黴素、哌拉西林他唑巴坦均敏感，頭孢他啶敏感率較高（90%），氨芐西林均耐藥。結論革蘭氏暘性菌和陰性菌所佔比例相噹，對氨芐西林均耐藥。革蘭氏暘性毬菌對萬古黴素敏感，革蘭氏陰性菌對美洛培南、亞胺培南、丁胺卡那黴素、哌拉西林他唑巴坦敏感。
목적：탐토복막투석상관성복막염적치병균급세균내약정황，지도림상용약。방법회고성분석해복막투석중심2009년12월-2013년8월공70례복막염환자적복막투석류출액배양+약민결과。기중남성50례，녀성20례，년령21～77세，평균（46.8±26.3）세。결과기중복발3례，재발1례，약민배양양성23례，양성솔위38.3%，기중혁란씨양성균점10례（43.5%），혁란씨음성균12례（52.2%），진균1례（4.3%）；혁란양성구균대만고매소균민감，대청매소내약솔교고（80%），분서서림내약솔83.3%，홍매소내약솔100%；혁란음성균대미락배남、아알배남、정알잡나매소、고랍서림타서파탄균민감，두포타정민감솔교고（90%），안변서림균내약。결론혁란씨양성균화음성균소점비례상당，대안변서림균내약。혁란씨양성구균대만고매소민감，혁란씨음성균대미락배남、아알배남、정알잡나매소、고랍서림타서파탄민감。
Objective To explore the pathogenic bacteria of peritoneal dialysis related peritonitis and their drug resistance so as to guide the clinical medication. Methods The culture and result of drug susceptibility test of 70 cases of peritoneal dialysis effluent in our peritoneal dialysis center from December, 2009 to August, 2013 were analyzed retrospectively. Of the patients, there were 50 males, 20 females, aged from 21 to 77, the average age was 46.8±26.3. Results Among them, reoccurrence occurred in 3 cases, relapse occurred in 1 case, 23 cases of positive drug susceptibility, the positive rate was 38.3%; including 10 cases of gram-posi-tive bacteria (43.5%), 12 cases of gram-negative bacteria (52.2%), 1 case of fungus (4.3%);gram-positive bacteria were sensitive to vancomycin, the drug resistance rate of penicillin was as high as 80%, the resistance rate of oxacillin was 83.3%, that of ery-thromycin was 100%;gram-negative bacteria were sensitive to meropenem, imipenem, amikacin, piperacillin sodium and tazobac-tam sodium, the sensitive rate of ceftazidime was higher (90%), but were resistant to ampicillin. Conclusion The proportion of gram-positive bacteria and gram-negative bacteria is almost the same, both of them are resistant to ampicillin. Gram-positive bac-teria are sensitive to vancomycin, and gram-negative bacteria are sensitive to meropenem, imipenem, amikacin, piperacillin sodium and tazobactam sodium.
