CAJ | 학술논문

目的：探讨超敏C反应蛋白（hs-CRP）、脂蛋白a [LP （a）]的血清水平与再发急性心肌梗死的关系。方法选择再发急性心肌梗死（再梗组）18例；单纯心绞痛（ AP ）者23例为AP组，既往有一次心梗病史的陈旧性心肌梗死（ OMI）者20例为OMI组。分别测定、比较各组间hs-CRP、 LP （ a）的血清水平差异。结果 OMI组、 AP组、再梗组hs-CRP、 Lp （a）浓度逐渐升高，且各组间hs-CRP、 Lp （a）差异有统计学意义（P＜0.05）。再梗组Lp （a）和hs-CRP呈正相关性（r ＝0.697， P＜0.001）。结论（1）血清hs-CRP、 Lp （a）浓度升高与再发急性心肌梗死的发生有极大的相关性，是再发心梗的危险因素，在预测再发心梗方面具有一定的意义；（2）冠心病患者血清 Hs-CRP、 Lp （ a）水平随着病情的加重而相对增高，说明hs-CRP、 Lp （ a）与冠心病严重程度有相关性。
목적：탐토초민C반응단백（hs-CRP）、지단백a [LP （a）]적혈청수평여재발급성심기경사적관계。방법선택재발급성심기경사（재경조）18례；단순심교통（ AP ）자23례위AP조，기왕유일차심경병사적진구성심기경사（ OMI）자20례위OMI조。분별측정、비교각조간hs-CRP、 LP （ a）적혈청수평차이。결과 OMI조、 AP조、재경조hs-CRP、 Lp （a）농도축점승고，차각조간hs-CRP、 Lp （a）차이유통계학의의（P＜0.05）。재경조Lp （a）화hs-CRP정정상관성（r ＝0.697， P＜0.001）。결론（1）혈청hs-CRP、 Lp （a）농도승고여재발급성심기경사적발생유겁대적상관성，시재발심경적위험인소，재예측재발심경방면구유일정적의의；（2）관심병환자혈청 Hs-CRP、 Lp （ a）수평수착병정적가중이상대증고，설명hs-CRP、 Lp （ a）여관심병엄중정도유상관성。
Objective To investigate the relationship between hs-CRP, LP ( a) levels and acute myocardial reinfarction Meth-ods 61 cases (18 cases with acute myocardial reinfarction and 23 cases with angina pectoris and 20 cases with no symptoms) were enrolled.They were divided into three groups:reinfarction group, angina pectoris ( AP) group and OMI group.the hs-CRP and Lp ( a) in the serum of each groups were determined, and the differences of the results were compared.Results The consistency of hs-CRP and Lp ( a) among three groups ( OMI group , AP group, reinfarction group) gradually increased and was statistically significant (P<0.05).The relationship between serum Lp (a) and hs-CRP in reinfarction groups was positive (R=0.697, P<0.001).Con-clusions (1) These results suggest that the rise of the consistency of hs-CRP and LP (a) has strong associations with attack of a-cute myocardial reinfarction , risk factors of acute myocardial reinfarction , and they also have certain significances in predicting recur-rence of myocardial infarction.(2) The level of blood serum hs-CRP and LP (a) of the patients with coronary heart disease increase with the seriousness of the disease, which shows that there is a significant relevance in hs-CRP and Lp ( a) and the seriousness of the coronary heart disease.