CAJ | 학술논문

目的对一氧化碳中毒后迟发性脑病患者的临床特点进行分析。方法对我院2010年1月~2013年3月期间收治的56例一氧化碳中毒后引起的迟发性脑病患者的临床资料采用影像学检查及乳酸值对比的方法进行回顾性分析。结果56例一氧化碳中毒迟发性脑病患者的临床症状表现差异较大。主要表现为大小便失禁和行为异常，占91.1%；经过CT检查，患者基底节区发生大范围低密度坏死灶，占94.1%；经头颅MIR影像观察，基底节区或者脑白质发生病变的患者占100%；血乳酸大于5 mmol/L的患者占62.5%；昏迷时间大于12 h；年龄＞50岁以及具有伴发病等因素，都是引起迟发性脑病的病因。结论导致一氧化碳中毒迟发性脑病出现的原因有多种，在临床治疗中，应该对这些影响因素进行重视。
목적대일양화탄중독후지발성뇌병환자적림상특점진행분석。방법대아원2010년1월~2013년3월기간수치적56례일양화탄중독후인기적지발성뇌병환자적림상자료채용영상학검사급유산치대비적방법진행회고성분석。결과56례일양화탄중독지발성뇌병환자적림상증상표현차이교대。주요표현위대소편실금화행위이상，점91.1%；경과CT검사，환자기저절구발생대범위저밀도배사조，점94.1%；경두로MIR영상관찰，기저절구혹자뇌백질발생병변적환자점100%；혈유산대우5 mmol/L적환자점62.5%；혼미시간대우12 h；년령＞50세이급구유반발병등인소，도시인기지발성뇌병적병인。결론도치일양화탄중독지발성뇌병출현적원인유다충，재림상치료중，응해대저사영향인소진행중시。
Objective To analyze and discuss the clinical characteristics of patients with delayed encephalopathy after carbon monoxide poisoning. Methods The clinical data of 56 cases of patients with delayed encephalopathy due to carbon monoxide poisoning were analyzed retrospectively by imageological diagnosis and lactic acid value comparison, from January 2010 to March 2013 in our hospital. Results The clinical symptoms were quite different in 56 cases of patients with delayed encephalopathy after carbon monoxide poisoning, which could mainly be seen incontinence and abnormal behavior, accounting for 91.1%; there was widespread low-density necrosis foci occurring in basal ganglia area by CT, accounting for 94.1%; the lesions occurred in basal ganglia region or white matter by head MRI imaging observation, accounting for 100%; blood lactic acid was greater than 5 mmol/L, accounted for 62.5%; it was the cause of delayed encephalopathy, including coma for more than 12 hours, older than 50 years old and concomitant disease and other factors. Conclusion There is a variety of reasons that may cause carbon monoxide poisoning delayed encephalopathy. We should pay attention to these factors in clinical treatment.