CAJ | 학술논문

目的：讨论吸入性药物在妊娠期支气管哮喘轻中度急性发作中的临床治疗效果。方法：将45例支气管哮喘孕妇随机分为三组：沙丁组、沙异组、沙布组，每组15例，沙丁组给予沙丁胺醇雾化吸入，另两组在沙丁组基础上分别加用异丙托溴胺、布地奈德吸入剂。结果：沙丁组与沙异组、沙布组治疗后各指标比较，差异有统计学意义(P＜0.05)；沙异组与沙布组治疗后比较，差异无统计学意义(P＞0.05)。结论：妊娠合并支气管哮喘轻中度急性发作时，吸入β2受体激动剂加抗胆碱药物能有效缓解气道的痉挛，减少炎性细胞介质的释放，从而改善患者临床症状。
목적：토론흡입성약물재임신기지기관효천경중도급성발작중적림상치료효과。방법：장45례지기관효천잉부수궤분위삼조：사정조、사이조、사포조，매조15례，사정조급여사정알순무화흡입，령량조재사정조기출상분별가용이병탁추알、포지내덕흡입제。결과：사정조여사이조、사포조치료후각지표비교，차이유통계학의의(P＜0.05)；사이조여사포조치료후비교，차이무통계학의의(P＞0.05)。결론：임신합병지기관효천경중도급성발작시，흡입β2수체격동제가항담감약물능유효완해기도적경련，감소염성세포개질적석방，종이개선환자림상증상。
Objective:To discuss the clinical therapeutic effect of inhaled drugs in pregnancy bronchial asthma.Methods:45 cases of bronchial asthma in pregnant women were randomly divided into 3 groups:Salbutamol group,salbutamol+ipratropium bromide group,salbutamol+budesonide group,15 cases in each group.The salbutamol group were given salbutamol,and the other two groups were given ipratropium bromide and budesonide inhalation respectively based on the salbutamol group.Results:We compared the index of 3 groups after the treatment,and there was statistically significant(P<0.05).We compared the salbutamol+ipratropium bromide group and the salbutamol+budesonide group,and there was no significant difference(P>0.05).Conclusion:The pregnancy complicated with bronchial asthma,the inhalation of β2 receptor agonist and anticholinergic drugs can relieve airway spasm and reduce inflammatory mediator release,so it can improve the clinical symptoms of patients.