中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
18期
25-26
,共2页
辛伐他汀%美托洛尔%慢性心力衰竭%6分钟步行试验%C反应蛋白
辛伐他汀%美託洛爾%慢性心力衰竭%6分鐘步行試驗%C反應蛋白
신벌타정%미탁락이%만성심력쇠갈%6분종보행시험%C반응단백
Simvastatin%Metoprolol%Chronic heart failure%6 minute walk test%Creactive protein
目的:观察美托洛尔联合辛伐他汀治疗慢性心力衰竭的疗效。方法:将84例慢性心力衰竭患者随机分为治疗组和对照组,对照组采用一般基础治疗(ACEI、利尿剂、洋地黄类),治疗组在一般治疗基础上加用辛伐他汀及美托洛尔治疗。在治疗前后比较临床症状、心功能分级、6分钟步行试验、心脏彩色多普勒超声、C反应蛋白(CRP)、心率、血压等。结果:与对照组比较,治疗组心功能好转,6分钟步行试验距离延长,E/A 增加,CRP 明显下降,心率、血压下降,差异有统计学意义(P<0.05)。结论:在常规治疗慢性心力衰竭的同时,加用辛伐他汀、美托洛尔能进一步提高临床疗效和改善远期预后和提高患者生活质量。
目的:觀察美託洛爾聯閤辛伐他汀治療慢性心力衰竭的療效。方法:將84例慢性心力衰竭患者隨機分為治療組和對照組,對照組採用一般基礎治療(ACEI、利尿劑、洋地黃類),治療組在一般治療基礎上加用辛伐他汀及美託洛爾治療。在治療前後比較臨床癥狀、心功能分級、6分鐘步行試驗、心髒綵色多普勒超聲、C反應蛋白(CRP)、心率、血壓等。結果:與對照組比較,治療組心功能好轉,6分鐘步行試驗距離延長,E/A 增加,CRP 明顯下降,心率、血壓下降,差異有統計學意義(P<0.05)。結論:在常規治療慢性心力衰竭的同時,加用辛伐他汀、美託洛爾能進一步提高臨床療效和改善遠期預後和提高患者生活質量。
목적:관찰미탁락이연합신벌타정치료만성심력쇠갈적료효。방법:장84례만성심력쇠갈환자수궤분위치료조화대조조,대조조채용일반기출치료(ACEI、이뇨제、양지황류),치료조재일반치료기출상가용신벌타정급미탁락이치료。재치료전후비교림상증상、심공능분급、6분종보행시험、심장채색다보륵초성、C반응단백(CRP)、심솔、혈압등。결과:여대조조비교,치료조심공능호전,6분종보행시험거리연장,E/A 증가,CRP 명현하강,심솔、혈압하강,차이유통계학의의(P<0.05)。결론:재상규치료만성심력쇠갈적동시,가용신벌타정、미탁락이능진일보제고림상료효화개선원기예후화제고환자생활질량。
Objective:To observe the curative effect of metoprolol combined with simvastatin in the treatment of chronic heart failure.Methods:84 cases with chronic heart failure were randomly divided into the treatment group and the control group.The control group were given general therapy(ACEI,diuretics,digitalis),and the treatment group were added with simvastatin and metoprolol on the basis of general treatment.Compare the clinical symptoms and determined cardiac functional grading,6 minute walk testing,heart color doppler ultrasound,C reactive protein(CRP),heart rate,blood pressure before and after treatment.Results:Compared with the control group,heart function improved in the treatment group,testing distance of the 6 minute walk prolonged,E/A increased,CRP decreased,heart rate and blood pressure decreased significantly(P<0.05).Conclusion:In the conventional treatment of chronic heart failure,adding simvastatin and metoprolol at the same time,can improve the prognosis of the clinical curative effect and improve the quality of life of the patients.