中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
18期
14-15
,共2页
米非司酮%乳酸依沙吖啶%卡前列甲酯栓%瘢痕子宫%引产效果
米非司酮%乳痠依沙吖啶%卡前列甲酯栓%瘢痕子宮%引產效果
미비사동%유산의사아정%잡전렬갑지전%반흔자궁%인산효과
Mifepristone%Ethacridine lactate%Carboprost methylate suppositorites%Uterine scar%Effect of induction of labor
目的：探索米非司酮联合依沙吖啶及卡前列甲酯栓终止妊娠中期瘢痕子宫的效果。方法：选择瘢痕子宫再次妊娠20～27周215例，随机分为研究组110例和对照组105例。研究组口服米非司酮25mg，服药150mg后经腹羊膜腔注入依沙吖啶100mg，产后肛塞卡前列甲酯栓；对照组单用依沙吖啶100 mg 经腹羊膜腔注入，产后肌注缩宫素。观察两组患者用药至胚胎娩出时间、胎盘娩出时间、产后2小时出血量及产后24小时出血量。结果：两组引产成功率比较差异无统计学意义(P＞0.05)。研究组用药至胚胎娩出时间、胎盘娩出时间、产后2小时出血量及产后24小时出血量均优于对照组，差异均有统计学意义(P＜0.05)。结论：妊娠中期瘢痕子宫引产在排除用药禁忌证后，采用米非司酮联合依沙吖啶及卡前列甲酯栓进行引产安全有效。
目的：探索米非司酮聯閤依沙吖啶及卡前列甲酯栓終止妊娠中期瘢痕子宮的效果。方法：選擇瘢痕子宮再次妊娠20～27週215例，隨機分為研究組110例和對照組105例。研究組口服米非司酮25mg，服藥150mg後經腹羊膜腔註入依沙吖啶100mg，產後肛塞卡前列甲酯栓；對照組單用依沙吖啶100 mg 經腹羊膜腔註入，產後肌註縮宮素。觀察兩組患者用藥至胚胎娩齣時間、胎盤娩齣時間、產後2小時齣血量及產後24小時齣血量。結果：兩組引產成功率比較差異無統計學意義(P＞0.05)。研究組用藥至胚胎娩齣時間、胎盤娩齣時間、產後2小時齣血量及產後24小時齣血量均優于對照組，差異均有統計學意義(P＜0.05)。結論：妊娠中期瘢痕子宮引產在排除用藥禁忌證後，採用米非司酮聯閤依沙吖啶及卡前列甲酯栓進行引產安全有效。
목적：탐색미비사동연합의사아정급잡전렬갑지전종지임신중기반흔자궁적효과。방법：선택반흔자궁재차임신20～27주215례，수궤분위연구조110례화대조조105례。연구조구복미비사동25mg，복약150mg후경복양막강주입의사아정100mg，산후항새잡전렬갑지전；대조조단용의사아정100 mg 경복양막강주입，산후기주축궁소。관찰량조환자용약지배태면출시간、태반면출시간、산후2소시출혈량급산후24소시출혈량。결과：량조인산성공솔비교차이무통계학의의(P＞0.05)。연구조용약지배태면출시간、태반면출시간、산후2소시출혈량급산후24소시출혈량균우우대조조，차이균유통계학의의(P＜0.05)。결론：임신중기반흔자궁인산재배제용약금기증후，채용미비사동연합의사아정급잡전렬갑지전진행인산안전유효。
Objective:To investigate the effect of mifepristone combined with ethacridine lactate and carboprost methylate suppositorites in terminating scar uterine mid pregnancy.Methods:215 cases with scar uterine pregnancy 20~27 weeks were selected.They were randomly divided into the study group with 110 cases and the control group with 105 cases.The study group were given oral mifepristone 25mg,injection of rivanol 100mg by transabdominal amniocentesis after taking 150mg medication, anal saika forefront of methyl suppository after delivery.The control group were only given injection of ethacridine 100 mg abdominal amniotic cavity and intramuscular injection of oxytocin after delivery. Observe the time from givening medication to embryo placental delivery,placental delivery time,amount of bleeding at 2 hours and 24 hours after delivery of two groups.Results:There was no statistically difference in the success rate of induced labor of two groups (P>0.05).The time from givening medication to embryo placental delivery,placental delivery time,amount of bleeding at 2 hours and 24 hours after delivery of the study group were better than that of the control group.The difference was statistically significant(P<0.05).Conclusion:Using of mifepristone combined with ethacridine lactate and carboprost methylate suppositorites in mid-term pregnancy uterine scar induced labor was safe and effective,after exclusion of medication contraindications.
