CAJ | 학술논문

聚二甲基硅氧烷（PDMS）具有良好的化学稳定性和透光性，以及易加工，价格低廉等优点，广泛应用于微流控芯片领域。但是由于PDMS自身为表面高度疏水且多孔性材料，导致其对DNA、蛋白质等生物大分子具有强烈的非特异性吸附，限制了它的应用范围，需要对其进行表面修饰。PDMS表面修饰的方法众多，主要分为物理方法、化学方法两大类。概述了目前常用的几种PDMS表面修饰的方法。
취이갑기규양완（PDMS）구유량호적화학은정성화투광성，이급역가공，개격저렴등우점，엄범응용우미류공심편영역。단시유우PDMS자신위표면고도소수차다공성재료，도치기대DNA、단백질등생물대분자구유강렬적비특이성흡부，한제료타적응용범위，수요대기진행표면수식。PDMS표면수식적방법음다，주요분위물리방법、화학방법량대류。개술료목전상용적궤충PDMS표면수식적방법。
Polydimethylsiloxane （PDMS） is widely used in microfluidic, due to the stability, transparence, easy processing and low cost. However, is the high hydropho excellent chemical bicity and porosity of PDMS, which cause the strong adorability of biomolecule （ such as DNA, protein, etc. ） , limit its application. Commonly, the surface modification can make some improvement. Up to now, many methods have been developed on the modification of PDMS, which can be divided into physical and chemical modification. In the paper, several methods of modification were reviewed.