CAJ | 학술논문

目的：评价5-氨基酮戊酸光动力疗法对降低尖锐湿疣复发率的有效性。方法检索知网、万方和维普数据库中涉及尖锐湿疣的2009年至2013年年度文献,按照纳入研究标准筛选文献,并采用Stata/SE 11.0软件对质量较好的文献进行Meta分析。结果纳入9篇均为对比研究采用光动力疗法或者CO2激光治疗尖锐湿疣的文献,随机效应模型Meta分析显示5-氨基酮戊酸光动力疗法的复发率低于CO2激光疗法的复发率[OR=4.121,95%CI(3.162,5.374),P<0.01]。结论5-氨基酮戊酸光动力疗法确实可降低尖锐湿疣的复发率,但由于文献数量和质量有限,以上结论有待日后进一步验证。
목적：평개5-안기동무산광동력요법대강저첨예습우복발솔적유효성。방법검색지망、만방화유보수거고중섭급첨예습우적2009년지2013년년도문헌,안조납입연구표준사선문헌,병채용Stata/SE 11.0연건대질량교호적문헌진행Meta분석。결과납입9편균위대비연구채용광동력요법혹자CO2격광치료첨예습우적문헌,수궤효응모형Meta분석현시5-안기동무산광동력요법적복발솔저우CO2격광요법적복발솔[OR=4.121,95%CI(3.162,5.374),P<0.01]。결론5-안기동무산광동력요법학실가강저첨예습우적복발솔,단유우문헌수량화질량유한,이상결론유대일후진일보험증。
Objective To analyze availability of 5-aminolevulinic acid photodynamic therapy (5-5-ALA PDT) in reducing the relapse rate of condyloma acuminatum. Methods Literatures involved in condyloma acuminatum from year 2009 to 2013 were searched in CNKI, Wanfang-data or CQVIP database and screened based on researching standards. The literatures of better quality were meta-analyzed using Stata/SE11. 0 software. Results Nine litera-tures involved in 5-ALA-PDT or CO2 laser treatment on condyloma acuminatum were selected. Meta-analysis of ran-dom effects model have shown that relapse rate of condyloma acuminatum under 5-ALA-PDT was lower than that of condyloma acuminatum under CO2 laser therapy [OR=4. 121, 95%CI(3. 16, 5. 37), P<0. 01]. Conclusion 5-ALA-PDT can reduce relapse rate of condyloma acuminatum, which need to be further validated due to the limited quantity and quality of literatures.