国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
15期
2298-2300
,共3页
梗阻性无精子症%经皮附睾精子抽吸术%睾丸精子抽吸术%卵胞浆内单精子注射
梗阻性無精子癥%經皮附睪精子抽吸術%睪汍精子抽吸術%卵胞漿內單精子註射
경조성무정자증%경피부고정자추흡술%고환정자추흡술%란포장내단정자주사
Obstructive azoospermia%Percutaneous epididymal sperm aspiration%Testicular sperm aspiration%Intracytoplasmic sperm injection
目的 比较梗阻性无精子症应用附睾精子与睾丸精子行卵胞浆内单精子注射技术(ICSI)的临床结局.方法 回顾分析2011年及2012年梗阻性无精子症患者于我中心ICSI助孕110周期,根据精子来源,分为附睾精子组(PESA组)及睾丸精子组(TESA组),比较两组间的2PN受精率、卵裂率、可移植胚胎率、临床妊娠率、流产率等.结果 2PN受精率TESA组(77.8％)明显低于PESA组(84.5％)(P＜0.05).TESA组与PESA组的卵裂率(97.1％、97.6％)、可移植胚胎率(74.4％、70.7％)、临床妊娠率(78.6％、67.1％)、流产率(4.6％、7.3％),两组比较差异均无统计学意义(P＞0.05).结论 TESA精子用于ICSI治疗2PN受精率比PESA精子低,TESA精子与PESA精子妊娠结局无显著差异.
目的 比較梗阻性無精子癥應用附睪精子與睪汍精子行卵胞漿內單精子註射技術(ICSI)的臨床結跼.方法 迴顧分析2011年及2012年梗阻性無精子癥患者于我中心ICSI助孕110週期,根據精子來源,分為附睪精子組(PESA組)及睪汍精子組(TESA組),比較兩組間的2PN受精率、卵裂率、可移植胚胎率、臨床妊娠率、流產率等.結果 2PN受精率TESA組(77.8％)明顯低于PESA組(84.5％)(P＜0.05).TESA組與PESA組的卵裂率(97.1％、97.6％)、可移植胚胎率(74.4％、70.7％)、臨床妊娠率(78.6％、67.1％)、流產率(4.6％、7.3％),兩組比較差異均無統計學意義(P＞0.05).結論 TESA精子用于ICSI治療2PN受精率比PESA精子低,TESA精子與PESA精子妊娠結跼無顯著差異.
목적 비교경조성무정자증응용부고정자여고환정자행란포장내단정자주사기술(ICSI)적림상결국.방법 회고분석2011년급2012년경조성무정자증환자우아중심ICSI조잉110주기,근거정자래원,분위부고정자조(PESA조)급고환정자조(TESA조),비교량조간적2PN수정솔、란렬솔、가이식배태솔、림상임신솔、유산솔등.결과 2PN수정솔TESA조(77.8％)명현저우PESA조(84.5％)(P＜0.05).TESA조여PESA조적란렬솔(97.1％、97.6％)、가이식배태솔(74.4％、70.7％)、림상임신솔(78.6％、67.1％)、유산솔(4.6％、7.3％),량조비교차이균무통계학의의(P＞0.05).결론 TESA정자용우ICSI치료2PN수정솔비PESA정자저,TESA정자여PESA정자임신결국무현저차이.
Objective To compare treatment effects of intracytoplasmic sperm injection (ICSI) outcomes using epididymal and testicular spermatozoa in men with obstructive azoospermia.Methods This study retrospectively analyzed 110 azoospermic patients with ICSI cycles who were divided into percutaneous epididymal sperm aspiration (PESA) group and testicular sperm aspiration (TESA) group by the source of sperm.Two groups were compared in the rates of fertilization,cleavage,embryo quality,clinical pregnancy and fetal abortion.Results The 2PN fertilization rate was significantly lower in the TESA group than that in the PESA group (77.8％,84.5％,P ＜ 0.05).But no statistical significant differences were observed in the rates of cleavage (97.1％,97.6％),embryo quality (74.4％,70.7％),clinical pregnancy (78.6％,67.1％),fetal abortion (4.6％,7.3％) (P ＞ 0.05).Conclusion TESA-obtained sperm has a lower 2PN fertilization rate than PESA-obtained sperm,both of them have similar pregnancy outcomes.
