CAJ | 학술논문

目的及时掌握布氏杆菌病的流行动态，为制定防制措施提供依据。方法对确诊187例布氏杆菌病患者进行流行病学调查，并对临床资料进行分析，采用布氏杆菌凝聚试管法进行抗体滴度检测。结果确山县布氏杆菌病呈现暴发流行态势，病例主要集中在该县竹沟镇（占51.4%），向周边乡镇辐射；患者以30～60岁青壮年居多，占81.3%，平均年龄（45.4±4.7）岁，男女比为3.16︰1。每年4~5月份为发病高峰期，职业分布以梳绒感染为主；23.2%有接触史的患者在接触时采取防护措施；临床特点以发热、乏力、多汗、肌肉酸痛、骨关节痛、食欲减退为主要表现，关节受累以腰、膝负重关节为主，7.5%的患者伴有肝功能异常。结论确山县及其周边地区布氏杆菌病疫情呈现局部暴发流行，应加大布氏杆菌病的防控力度。
목적급시장악포씨간균병적류행동태，위제정방제조시제공의거。방법대학진187례포씨간균병환자진행류행병학조사，병대림상자료진행분석，채용포씨간균응취시관법진행항체적도검측。결과학산현포씨간균병정현폭발류행태세，병례주요집중재해현죽구진（점51.4%），향주변향진복사；환자이30～60세청장년거다，점81.3%，평균년령（45.4±4.7）세，남녀비위3.16︰1。매년4~5월빈위발병고봉기，직업분포이소융감염위주；23.2%유접촉사적환자재접촉시채취방호조시；림상특점이발열、핍력、다한、기육산통、골관절통、식욕감퇴위주요표현，관절수루이요、슬부중관절위주，7.5%적환자반유간공능이상。결론학산현급기주변지구포씨간균병역정정현국부폭발류행，응가대포씨간균병적방공력도。
Objective To grasp timely the epidemic dynamics of brucellosis in order to provide the basis for the establishment of prevention and control measures. Methods The epidemiological investigation and clinical data analysis of 187 cases with brucellosis were carried out. The antibody titer was tested by brucella condensation tube method. Results Brucellosis presented outbreak epidemic situation in Queshan county. The cases were mainly concentrated in Zhugou town of the county(51.4%),and radiated to the surrounding villages and towns. The patients were mostly 30 to 60 years young that accounted for 81.3%. The average age was(45.4±4.7) years old. The sex ratio of male and female was 3.16︰1. The onset of peak time were appeared April to May each year. Many of the infected persons mainly engaged in cashmere comb. Only 23.2%of patients with a history of exposure took protective measures. The main clinical manifestation were fever,fatigue,sweating,muscle aches,bone and joint pain and loss of appetite. The joint involvement were mainly in the waist,knee-based weight-bearing joints. 7.5%of the patients had abnormal liver function. Conclusion It shows that brucellosis appear localized outbreaks in Queshan county and its surrounding areas. It is necessary to strengthen the prevention and control of brucellosis.