中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2014年
1期
59-61
,共3页
Vogt-小柳-原田综合征%黄斑水肿%预后
Vogt-小柳-原田綜閤徵%黃斑水腫%預後
Vogt-소류-원전종합정%황반수종%예후
Vogt-Koyanagi-Harada syndrome%Macular edema%Prognosis
目的 探讨Vogt-小柳-原田综合征(VKHs)患者急性期黄斑区视网膜神经纤维层脱离、水肿对视力预后的影响.方法 回顾性分析2006年12月至2009年1月在中山大学中山眼科中心就诊的VKHs初发患者74例(108眼)的黄斑部病变情况及治疗前、后患者的视力分布,比较有和无黄斑部脱离、水肿的患者治疗后的视力.结果 74例VKHs患者中,有黄斑部脱离、水肿的患者53例(71.62％),无黄斑部脱离、水肿的患者21例(28.38％).有黄斑部脱离、水肿者,发病时视力下降主要集中在0.01～＜0.5的视力段范围;而无黄斑部脱离、水肿者,发病时视力下降主要集中在0.1～＜0.5的视力段范围.急性期有和无黄斑部脱离、水肿的患者治疗后视力≥1.0的比例分别为86.79％ (46/53)和100％(21/21),差异无统计学意义(P＞0.05).结论 VKHs患者急性期无论是否出现黄斑部病变,进行及时有效地治疗后不影响视力预后.
目的 探討Vogt-小柳-原田綜閤徵(VKHs)患者急性期黃斑區視網膜神經纖維層脫離、水腫對視力預後的影響.方法 迴顧性分析2006年12月至2009年1月在中山大學中山眼科中心就診的VKHs初髮患者74例(108眼)的黃斑部病變情況及治療前、後患者的視力分佈,比較有和無黃斑部脫離、水腫的患者治療後的視力.結果 74例VKHs患者中,有黃斑部脫離、水腫的患者53例(71.62％),無黃斑部脫離、水腫的患者21例(28.38％).有黃斑部脫離、水腫者,髮病時視力下降主要集中在0.01～＜0.5的視力段範圍;而無黃斑部脫離、水腫者,髮病時視力下降主要集中在0.1～＜0.5的視力段範圍.急性期有和無黃斑部脫離、水腫的患者治療後視力≥1.0的比例分彆為86.79％ (46/53)和100％(21/21),差異無統計學意義(P＞0.05).結論 VKHs患者急性期無論是否齣現黃斑部病變,進行及時有效地治療後不影響視力預後.
목적 탐토Vogt-소류-원전종합정(VKHs)환자급성기황반구시망막신경섬유층탈리、수종대시력예후적영향.방법 회고성분석2006년12월지2009년1월재중산대학중산안과중심취진적VKHs초발환자74례(108안)적황반부병변정황급치료전、후환자적시력분포,비교유화무황반부탈리、수종적환자치료후적시력.결과 74례VKHs환자중,유황반부탈리、수종적환자53례(71.62％),무황반부탈리、수종적환자21례(28.38％).유황반부탈리、수종자,발병시시력하강주요집중재0.01～＜0.5적시력단범위;이무황반부탈리、수종자,발병시시력하강주요집중재0.1～＜0.5적시력단범위.급성기유화무황반부탈리、수종적환자치료후시력≥1.0적비례분별위86.79％ (46/53)화100％(21/21),차이무통계학의의(P＞0.05).결론 VKHs환자급성기무론시부출현황반부병변,진행급시유효지치료후불영향시력예후.
Objective To investigate the impact of the detachment and edema of acute macular retinal nerve fiber layer on visual prognosis in patients with Vogt-Koyanagi-Harada syndrome(VKHs).Methods A retrospective analysis was performed on the macular lesions,visual distribution before and after treatment of 74 VKHs of the first attack patients (108 eyes) whom visited Zhongshan Ophthalmic Center,Sun Yat-sen University from December 2006 to January 2009.The post-treatment vision of the patients with or without macular detachment and edema were compared.Results There were 53 patients with macular detachment and edema (71.62％),and 21 patients without (28.38％) in 74 VKHs patients.The incipient hypopsia of the VKHs patients with macular detachment and edema was mainly distributed over 0.01 to ＜0.5,and 0.1 to ＜0.5 in patients without macular detachment and edema.The proportions of visual acuity ≥1.0 after treatment were 86.79％ (46/53) and 100％ (21/21) in VKHs patients of acute phase with or without macula detachment and edema (P＞0.05).Conclusion With timely and effectively treatment,the visual prognosis is not affected by the acute macular lesions in VKHs patients.
