CAJ | 학술논문

目的调查分析某院I类切口手术（甲状腺手术、乳腺手术、腹股沟斜疝修补术、闭合性骨折内固定术）围手术期抗菌药物预防应用情况，规范抗菌药物临床应用行为，提高合理用药水平。方法采用回顾性调查方法，随机抽取某院2011年1~12月416例4种I类切口手术病历资料进行统计分析。结果416例患者中，抗菌药物预防性应用率达99.5%，其中术前0.5~2 h应用的仅为60例（占14.4%），术前＞2 h的354例（占85.1%）。术后应用时间24~48 h的18例（占4.3%），＞48 h的396例（占95.2%）。预防性应用抗菌药物使用频次前4位分别为氨曲南、头孢硫脒、头孢替安、头孢唑肟。结论某院4种I类切口手术预防性应用抗菌药物存在不合理现象，应引起重视，加强监督管理，落实到位。
목적조사분석모원I류절구수술（갑상선수술、유선수술、복고구사산수보술、폐합성골절내고정술）위수술기항균약물예방응용정황，규범항균약물림상응용행위，제고합리용약수평。방법채용회고성조사방법，수궤추취모원2011년1~12월416례4충I류절구수술병력자료진행통계분석。결과416례환자중，항균약물예방성응용솔체99.5%，기중술전0.5~2 h응용적부위60례（점14.4%），술전＞2 h적354례（점85.1%）。술후응용시간24~48 h적18례（점4.3%），＞48 h적396례（점95.2%）。예방성응용항균약물사용빈차전4위분별위안곡남、두포류미、두포체안、두포서우。결론모원4충I류절구수술예방성응용항균약물존재불합리현상，응인기중시，가강감독관리，락실도위。
To investigate and analyze the perioperative antibiotic prophylaxis application in type Ⅰ incision (thyroid surgery, breast surgery, inguinal hernia repair, the closed reduction and internal fixation for fractures), regularize the behaviour of antibiotic clinical application, improve the rational drug use levels. Methods: 416 cases with four kinds of type Ⅰ incision w er from the patients from January to December 2011. Results: Preventive application of antibiotics occurred in 99.5% of 416 cases, only 60 cases (14.4%) 0.5~2 h before operation, 354 cases (85.1%) over 2 h before operation, 18 cases (4.3%) 24~48 h after operation, 396 cases (95.2%) over 48h after operation. The top four preventive medicines were aztreonam, cefathiamidine, cefotiam, and ceftizoxime. Conclusion: Irrational preventive medication of antibacterials in patients with four kinds of type Ⅰ incision is e more attention should be paid, supervision and management should be strengthened.