CAJ | 학술논문

目的探讨无冠心病症状人群使用超声波评估颈动脉内膜-中层厚度(IMT)与冠状动脉CT造影(CTA)检出动脉粥样硬化斑块的相关性.方法选择250例健康检查者作为研究对象,给予冠状动脉CTA筛查,根据检查结果分为未检出冠状动脉粥样硬化斑块180例(无斑块组)和检出冠状动脉粥样硬化斑块70例(斑块组).同时采用高频超声波测量所有研究对象的颈动脉IMT.结果 ANOVAs分析显示年龄与冠状动脉粥样硬化斑块形成显著相关(P＜0.05).x2检验显示吸烟史、冠心病家族史与冠状动脉粥样硬化斑块形成显著相关(P＜0.05).单变量Logistic回归分析显示颈动脉IMT、收缩压、舒张压、低密度脂蛋白胆固醇、空腹血糖、肌酐与冠状动脉粥样硬化斑块形成显著相关(P＜0.05).将所有冠状动脉粥样硬化危险标记物带人多因素Logistic回归方程分析,结果显示颈动脉IMT与冠状动脉粥样硬化斑块形成呈独立相关性(P＜0.05).结论无冠心病症状人群颈动脉IMT与冠状动脉CTA检出冠状动脉粥样硬化斑块显著相关.
목적 탐토무관심병증상인군사용초성파평고경동맥내막-중층후도(IMT)여관상동맥CT조영(CTA)검출동맥죽양경화반괴적상관성.방법 선택250례건강검사자작위연구대상,급여관상동맥CTA사사,근거검사결과분위미검출관상동맥죽양경화반괴180례(무반괴조)화검출관상동맥죽양경화반괴70례(반괴조).동시채용고빈초성파측량소유연구대상적경동맥IMT.결과 ANOVAs분석현시년령여관상동맥죽양경화반괴형성현저상관(P＜0.05).x2검험현시흡연사、관심병가족사여관상동맥죽양경화반괴형성현저상관(P＜0.05).단변량Logistic회귀분석현시경동맥IMT、수축압、서장압、저밀도지단백담고순、공복혈당、기항여관상동맥죽양경화반괴형성현저상관(P＜0.05).장소유관상동맥죽양경화위험표기물대인다인소Logistic회귀방정분석,결과현시경동맥IMT여관상동맥죽양경화반괴형성정독립상관성(P＜0.05).결론 무관심병증상인군경동맥IMT여관상동맥CTA검출관상동맥죽양경화반괴현저상관.
Objective To investigate the relationship between carotid intima-media thickness (IMT) and coronary atherosclerosis plaque through coronary CT angiography (CTA) in asymptomatic individuals.Methods Two hundred and fifty cases with CTA screened were selected in asymptomatic individuals,and according to the inspection result they were divided into no plaque group (detection of no coronary atherosclerosis plaque,180 cases) and plaque group (detection of coronary atherosclerosis plaque,70 cases).All cases were checked carotid IMT with B-ultrasonic.Results ANOVAs analysis showed that age and body mass index (BMI) had significant correlation with coronary atherosclerosis plaque (P ＜ 0.05).x2 test was used to show the smoking and family history of coronary heart disease had significant correlation with coronary atherosclerosis plaque (P ＜ 0.05).Univariate Logistic regression analysis showed that carotid IMT,systolic pressure,diastolic pressure,low density lipoprotein cholesterol,fasting serum glucose and creatinine had significant correlation with coronary atherosclerosis plaque (P ＜ 0.05).Multifactor Logistic regression analysis showed that carotid IMT had correlation with coronary atherosclerosis plaque (P ＜ 0.05).Conclusion There is significant relationship between carotid IMT and coronary atherosclerosis plaque in asymptomatic individuals.