CAJ | 학술논문

目的研究多囊卵巢综合征(PCOS)患者血清维生素D浓度同内分泌紊乱的相互关系。方法选取我院78例PCOS患者作为病例组，另选20例健康育龄期妇女作为对照组，计算体重指数(BMI)，测定血清睾酮(T)、雌二醇(E2)、LH、FSH及血清25-(OH)D3的浓度，并进行OGTT和胰岛素释放试验，计算QUICKI指数。结果病例组25-(OH)D3浓度与BMI、T、LH/FSH呈一定的负相关，与QUICKI值呈正相关。结论维生素D缺乏与PCOS内分泌紊乱密切相关，且维生素D的紊乱可能同时与患者肥胖具有一定的相关性。
목적연구다낭란소종합정(PCOS)환자혈청유생소D농도동내분비문란적상호관계。방법선취아원78례PCOS환자작위병례조，령선20례건강육령기부녀작위대조조，계산체중지수(BMI)，측정혈청고동(T)、자이순(E2)、LH、FSH급혈청25-(OH)D3적농도，병진행OGTT화이도소석방시험，계산QUICKI지수。결과병례조25-(OH)D3농도여BMI、T、LH/FSH정일정적부상관，여QUICKI치정정상관。결론유생소D결핍여PCOS내분비문란밀절상관，차유생소D적문란가능동시여환자비반구유일정적상관성。
Objective To study the patients with polycystic ovary syndrome serum vitamin D concentrations relationship with endocrine disorder. Methods Collected from 78 patients diagnosed with PCOS patients as case group, another 20 cases of healthy women of child-bearing age as controls, calculating body mass index(BMI), serum testosterone(T), estradiol(E2), LH, FSH and the concentration of serum 25-(OH)D3, and OGTT and insulin releasing test, QUICKI index is calculated. Results Cases group 25-(OH)D3 concentration with BMI, T, LH/FSH has certain negative correlation, and QUICKI values were positively correlated. Conclusion Vitamin D deficiency are closely associated with PCOS endocrine disorders, and disorders of vitamin D may also obesity has certain correlation with the patient.