浙江医学
浙江醫學
절강의학
ZHEJIANG MEDICAL JOURNAL
2013年
17期
1590-1592,1598
,共4页
肺癌%青年患者%临床特点%病理类型
肺癌%青年患者%臨床特點%病理類型
폐암%청년환자%림상특점%병리류형
Lung cancer%Young patients%Clinical features%Pathological type
目的分析青年人肺癌患者的临床及病理特征。方法收集2002-10-2012-10收治的116例经病理确诊的青年人肺癌患者的资料，并与同期收治的760例＞45岁的肺癌患者进行对比。结果116例青年人肺癌患者年龄分布为20～44岁，男女比例为1.5：1。青年组与中老年组早期临床症状均为咳嗽、痰中带血、胸闷，两组比较均无统计学差异(均P＞0.05)。青年组以肺外表现为首发症状和无任何症状的患者均多于中老年组(17.2% vs 10.1%，13.8%vs 5.4%，均P＜0.01）。青年人肺癌中腺癌居首位，其次为小细胞癌，均明显高于中老年组（60.3%vs 28.2%，19.0%vs 10.1%，均P＜0.01）。青年组晚期（Ⅲ～Ⅳ期）患者比例明显高于中老年组（78.4%vs 47.2%，P＜0.01）。青年组患者选择手术、化疗或者联合治疗的多于中老年组（P＜0.01）。结论青年人肺癌病理类型主要以腺癌和小细胞癌为主，晚期病例多，治疗上更积极，但预后较差。重视青年人肺癌患者的早期表现，及时行相应检查，有助于早期诊断和治疗。
目的分析青年人肺癌患者的臨床及病理特徵。方法收集2002-10-2012-10收治的116例經病理確診的青年人肺癌患者的資料，併與同期收治的760例＞45歲的肺癌患者進行對比。結果116例青年人肺癌患者年齡分佈為20～44歲，男女比例為1.5：1。青年組與中老年組早期臨床癥狀均為咳嗽、痰中帶血、胸悶，兩組比較均無統計學差異(均P＞0.05)。青年組以肺外錶現為首髮癥狀和無任何癥狀的患者均多于中老年組(17.2% vs 10.1%，13.8%vs 5.4%，均P＜0.01）。青年人肺癌中腺癌居首位，其次為小細胞癌，均明顯高于中老年組（60.3%vs 28.2%，19.0%vs 10.1%，均P＜0.01）。青年組晚期（Ⅲ～Ⅳ期）患者比例明顯高于中老年組（78.4%vs 47.2%，P＜0.01）。青年組患者選擇手術、化療或者聯閤治療的多于中老年組（P＜0.01）。結論青年人肺癌病理類型主要以腺癌和小細胞癌為主，晚期病例多，治療上更積極，但預後較差。重視青年人肺癌患者的早期錶現，及時行相應檢查，有助于早期診斷和治療。
목적분석청년인폐암환자적림상급병리특정。방법수집2002-10-2012-10수치적116례경병리학진적청년인폐암환자적자료，병여동기수치적760례＞45세적폐암환자진행대비。결과116례청년인폐암환자년령분포위20～44세，남녀비례위1.5：1。청년조여중노년조조기림상증상균위해수、담중대혈、흉민，량조비교균무통계학차이(균P＞0.05)。청년조이폐외표현위수발증상화무임하증상적환자균다우중노년조(17.2% vs 10.1%，13.8%vs 5.4%，균P＜0.01）。청년인폐암중선암거수위，기차위소세포암，균명현고우중노년조（60.3%vs 28.2%，19.0%vs 10.1%，균P＜0.01）。청년조만기（Ⅲ～Ⅳ기）환자비례명현고우중노년조（78.4%vs 47.2%，P＜0.01）。청년조환자선택수술、화료혹자연합치료적다우중노년조（P＜0.01）。결론청년인폐암병리류형주요이선암화소세포암위주，만기병례다，치료상경적겁，단예후교차。중시청년인폐암환자적조기표현，급시행상응검사，유조우조기진단화치료。
Objective To analyze the clinicopathologic characteristics of young patients with lung cancer. Methods One hundred and sixteen patients aged 20~44 with primary lung cancer (young group) admitted at Zhejiang Provincial People's Hospital from 2002 to 2012 and 760 lung cancer patients aged≥45 (older group) admitted at same period were enrol ed in the study. The clinicopathological data were retrospectively analyzed and compared between two groups. Results There were no significant differences in main clinical symptoms (cough, hemoptysis and chest distress) between two groups. However, the rates of asymptomatic patients or with non- respiratory symptoms at admission in young group were higher than those in older group (17.2%vs 10.1%,13.8% vs 5.4%, both P<0.01). The rates of adenocarcinoma and smal cel lung cancer in young group were significantly higher than those in older group (60.3%vs 28.2%,19.0%vs 10.1%, P<0.01). Higher percentage of advanced stage in young group than in old group was observed (78.4% vs 47.2%, P<0.01). Surgery, chemotherapy or combined modality of treatment were more often applied to young patients than to older ones. Conclusion More adenocarcinoma and smal cel lung cancer with advanced stage, aggressive treatment and worse prognosis are observed among young patients with lung cancer than in older patients.
