CAJ | 학술논문

目的：调查分析我院手术患者围手术期预防性使用抗菌药物情况及合理性，为临床医生合理用药提供依据。方法：根据卫生部指定的病历号，遴选出我院2013年1-12月出院且术前均无感染的手术患者59例，其中男32例，女27例；平均年龄42．5岁，最小5个月，最大77岁。结果：围手术期抗菌药预防用药率达100％，主要涉及抗菌药8类44种；术后单一用药9例，占总数的15．25％，联合用药50例，占总数的84．75，其中二联24例，占联合用药的48.00％，三联及以上用药26例，占联合用药的52.00％。使用率前3位的是左氧氟沙星注射液、氨曲南针和注射用头孢硫脒。结论：我院围手术期预防性使用抗菌药物存在用药指征把握不严、抗菌药物种类选择欠妥、盲目联合用药、给药时间不当和用药时间过长等问题，今后要加强抗菌药物管理，有效促进围手术期抗菌药物的合理应用。
목적：조사분석아원수술환자위수술기예방성사용항균약물정황급합이성，위림상의생합리용약제공의거。방법：근거위생부지정적병력호，린선출아원2013년1-12월출원차술전균무감염적수술환자59례，기중남32례，녀27례；평균년령42．5세，최소5개월，최대77세。결과：위수술기항균약예방용약솔체100％，주요섭급항균약8류44충；술후단일용약9례，점총수적15．25％，연합용약50례，점총수적84．75，기중이련24례，점연합용약적48.00％，삼련급이상용약26례，점연합용약적52.00％。사용솔전3위적시좌양불사성주사액、안곡남침화주사용두포류미。결론：아원위수술기예방성사용항균약물존재용약지정파악불엄、항균약물충류선택흠타、맹목연합용약、급약시간불당화용약시간과장등문제，금후요가강항균약물관리，유효촉진위수술기항균약물적합리응용。
To provide reasonable reference for clinical medication ,the prevention application of antibacterial used in perioperation period in our hospital were analyzed .Methods:59 patients (32 males and 27 females ,mean age 42.5 years ranged from 5 months to 77 years) free from preoperative infection and discharged from our hospital from January to December 2012 were participated in this study .Results:The incidence of antibiotic used round surgical operation period was 100% and 8 fami-lies (44 species) of antibacterials were mainly involved .As for the application of antibacterials after surgery ,single drug com-prised 15 .25% (9 cases) ,two-drug 48.00% (24 cases) and three-drug 52.00% (26 cases) .The 3 top application rates are levo-floxacin ,aztreonam and cefathiamidine injection .Conclusion:Because of taking medicine absurdly ,improperly selecting antimi-crobial drugs ,incorrectly combining drug and longer drug duration ,it is necessary to strengthen antimicrobials administration and rational use of antimicrobials in perioperation period .