CAJ | 학술논문

目的：探索深圳市西部地区托幼机构儿童手足口病（Hand-Foot-Mouth Disease ，HFMD）发病的危险因素。方法：采用问卷调查的方式，对深圳市西部某幼儿园所有儿童回顾性调查其在过去3年间的 H FM D患病史，采用单因素和多因素Logistic回归分析，分析影响 HFMD 的主要危险因素。结果：363名调查对象中，HFMD患者为79名，此队列人群发病密度为72．5/1000人年。单因素分析发现6个暴露因素和 H FM D发生有关；多因素分析显示 H FM D有2个保护因素和2个危险因素，分别为：非深圳户口（O R＝0．55，95％ C I：0．32～0．95），自然分娩（O R＝0．56，95％CI：0．33～0．96），5岁以下儿童数为2人以上（OR＝4．84，95％ CI：1．26～18．54），和手足口病人密切接触（OR＝4．59，95％ CI：1．44～14．6）。结论：接触传播是HFMD传播方式之一，因此减少儿童与患者接触对于控制HFMD传播起到重要作用。此外，养成良好的卫生习惯，提倡自然分娩和增加纯母乳喂养对预防婴幼儿患H FM D 起到保护性作用。
목적：탐색심수시서부지구탁유궤구인동수족구병（Hand-Foot-Mouth Disease ，HFMD）발병적위험인소。방법：채용문권조사적방식，대심수시서부모유인완소유인동회고성조사기재과거3년간적 H FM D환병사，채용단인소화다인소Logistic회귀분석，분석영향 HFMD 적주요위험인소。결과：363명조사대상중，HFMD환자위79명，차대렬인군발병밀도위72．5/1000인년。단인소분석발현6개폭로인소화 H FM D발생유관；다인소분석현시 H FM D유2개보호인소화2개위험인소，분별위：비심수호구（O R＝0．55，95％ C I：0．32～0．95），자연분면（O R＝0．56，95％CI：0．33～0．96），5세이하인동수위2인이상（OR＝4．84，95％ CI：1．26～18．54），화수족구병인밀절접촉（OR＝4．59，95％ CI：1．44～14．6）。결론：접촉전파시HFMD전파방식지일，인차감소인동여환자접촉대우공제HFMD전파기도중요작용。차외，양성량호적위생습관，제창자연분면화증가순모유위양대예방영유인환H FM D 기도보호성작용。
To explore risk factors of hand-foot-mouth disease(HFMD) in western parts of Shenzheng city . Methods :Questionnaire survey was used to investigate the history of children with HFMD in past 3 years retrospective-ly in one nurseries and kindergartens in western parts of Shenzheng City .Univariate analysis and multi-logistic regres-sion analysis were used to analyze major risk factors of HFMD .Results:There were 79 HFMD cases in 363 study ob-jects with incidence of 72 .5/1 000 person-years ,Univariate analysis indicated that six exposure factors were related to the occurrence of HFMD ;Multivariate analysis showed that there were two protective factors and two risk factors con-cerned with the prevalence of HFMD ,and the factors were depicted as follow :non registered resident of Shenzheng city (OR=0 .55 ,95% CI:0 .32-0 .95) ,natural delivery (OR=0 .56 ,95% CI:0 .33~0 .96) ,intimate contact with the patients of HFMD(OR=4 .59 ,95% CI:1 .44~14 .6) ,more than two children in the family(OR=4 .84 ,95% CI:1 .26~18 .54) . Conclusion:Contact transmission was one way of HFMD infection ,so reducing children to contact with the patient would be effective to control HFMD spread .In addition ,developing good health habits ,advocating natural delivery and breastfeeding should protect infant and children from HFMD .