CAJ | 학술논문

目的分析影响直肠癌根治术后肝转移的危险因素。方法对本院2005年9月至2010年8月收治的97例患者进行回顾分析，分析肝转移发生的相关危险因素。结果比较未发生肝转移与发生肝转移患者的一般临床特征，发现年龄、血型、肝功能指标、肿瘤分化程度及肿瘤大小等差异均无统计学意义（P＞0．05），而两组浸润深度差异有统计学意义（P＜0．05），肝转移患者浸润深度较深，显示出该因素易引发术后肝转移。对出现肝转移患者的临床指征进行单因素回归分析，可见除淋巴结转移外（P＜0．05），Dukes分期、血管神经侵犯等均非影响直肠癌根治术后肝转移的独立危险因素（P＞0．05）。结论淋巴结转移情况及浸润深度是影响直肠癌根治术后肝转移的主要因素，出现淋巴结转移、肿瘤侵袭深度增加，则术后肝转移发生率上升。
목적분석영향직장암근치술후간전이적위험인소。방법대본원2005년9월지2010년8월수치적97례환자진행회고분석，분석간전이발생적상관위험인소。결과비교미발생간전이여발생간전이환자적일반림상특정，발현년령、혈형、간공능지표、종류분화정도급종류대소등차이균무통계학의의（P＞0．05），이량조침윤심도차이유통계학의의（P＜0．05），간전이환자침윤심도교심，현시출해인소역인발술후간전이。대출현간전이환자적림상지정진행단인소회귀분석，가견제림파결전이외（P＜0．05），Dukes분기、혈관신경침범등균비영향직장암근치술후간전이적독립위험인소（P＞0．05）。결론림파결전이정황급침윤심도시영향직장암근치술후간전이적주요인소，출현림파결전이、종류침습심도증가，칙술후간전이발생솔상승。
Objective To explore the risk factors of hepatic metastasis after radical resection of rectal cancer . Methods Clinical data of 97 patients ,receiving radical resection of rectal cancer during Sep .2005 and Aug .2010 in this hospital ,were retrospectively analyzed to identify risk factors of hepatic metastasis .Results Between patients with or without hepatic metastasis ,the differences of age ,blood type ,liver function ,differentiation degree of cancer and primary lesion size were all without statistical significance (P>0 .05) ,but the difference of invasion depth was significant (P<0 .05) .Single factor analysis indicated that ,except lymph node metastasis (P<0 .05) ,other fac-tors ,such as Dukes stage ,vascular nerve invasion and so on ,were not independent factors influencing hepatic me-tastasis (P>0 .05) .Conclusion Lymph node metastasis and invasion depth could be the factors influencing hepatic metastasis after radical resection of rectal carcinoma .The rate of liver metastasis could be increased with lymph node metastasis and the increasing of invasion depth .