CAJ | 학술논문

目的了解温州地区育龄期妇女及孕妇弓形虫感染情况，为预防弓形虫先天性感染提供参考资料。方法收集577份婚前体检的育龄期妇女及229份孕妇体检静脉血标本，分离血清，采用间接酶联免疫吸附试验（ELISA）检测弓形虫特异性抗体 IgG和IgM ，以OD490≥cut off值定为阳性。结果577份育龄期妇女血清中弓形虫特异性抗体Ig G阳性标本452例，阳性率为78．34％；弓形虫特异性抗体Ig M 阳性标本3例，阳性率为0．52％。229份孕妇血清中弓形虫特异性抗体IgG阳性标本171例，阳性率为74．67％；弓形虫特异性抗体IgM阳性标本16例，阳性率为6．99％。结论温州地区妇女人群（育龄期妇女和孕妇）弓形虫隐性感染较为普遍，而孕妇Ig M 抗体阳性的新近感染率明显高于育龄期妇女。
목적료해온주지구육령기부녀급잉부궁형충감염정황，위예방궁형충선천성감염제공삼고자료。방법수집577빈혼전체검적육령기부녀급229빈잉부체검정맥혈표본，분리혈청，채용간접매련면역흡부시험（ELISA）검측궁형충특이성항체 IgG화IgM ，이OD490≥cut off치정위양성。결과577빈육령기부녀혈청중궁형충특이성항체Ig G양성표본452례，양성솔위78．34％；궁형충특이성항체Ig M 양성표본3례，양성솔위0．52％。229빈잉부혈청중궁형충특이성항체IgG양성표본171례，양성솔위74．67％；궁형충특이성항체IgM양성표본16례，양성솔위6．99％。결론온주지구부녀인군（육령기부녀화잉부）궁형충은성감염교위보편，이잉부Ig M 항체양성적신근감염솔명현고우육령기부녀。
Objective To learn about the population with in of fection toxoplasma gondii (T .gondii) in child-bearing age or pregnant women in Wenzhou area ,and to offer reference data for prevention of congenital infection caused by T .gondii .Methods Blood samples were collected from 577 samples of premarital physical examination in women of childbearing age and 229 samples of pregnant women .Serum were separated and detected T .gondii specific IgG and IgM by indirect enzyme linked immunosorbent assay (ELISA) .Positive were determined as OD490 more than cutoff value .Results A total of 452 cases of serum samples were positive for T .gondii specific IgG in 577 samples from women of child-bearing age ,which positive rate was 78 .34% ,while 3 cases were positive for T .gondii specific IgM ,which positive rate was 0 .52% .171 cases of serum samples were positive for T .gondii specific IgG in 229 sam-ples from pregnant women ,which positive rate was 74 .67% ,while 16 cases were positive for T .gondii specific IgM , which positive rate was 6 .99% .Conclusion Women in Wenzhou area (for child-bearing age or pregnant) with silent infection of T .gondii might be widespread ,and recent infection rate in pregnant women with IgM positive could be higher than women of child-bearing age .