CAJ | 학술논문

1例71岁女性患者因怀疑院内感染给予亚胺培南西司他丁钠0.5g,1次/8 h静脉滴注.第3天,患者突然出现抽搐、角弓反张、牙关紧闭,伴意识欠清、喘憋,持续约2 ～3 min,未予处理自行缓解.约15 min后上述症状再现,1～2 min后自行恢复正常.约75 min及2h后症状再发,持续时间为3～5 min,两次均给予地西泮及醒脑静.第4次发作后约50 min上述症状再次发作,给予苯巴比妥效果欠佳,换用丙戊酸钠400 mg静脉泵入.约1h后患者安静入睡.次日停用业胺培南西司他丁钠,改为拉氧头孢钠,患者未再出现抽搐.
1례71세녀성환자인부의원내감염급여아알배남서사타정납0.5g,1차/8 h정맥적주.제3천,환자돌연출현추휵、각궁반장、아관긴폐,반의식흠청、천별,지속약2 ～3 min,미여처리자행완해.약15 min후상술증상재현,1～2 min후자행회복정상.약75 min급2h후증상재발,지속시간위3～5 min,량차균급여지서반급성뇌정.제4차발작후약50 min상술증상재차발작,급여분파비타효과흠가,환용병무산납400 mg정맥빙입.약1h후환자안정입수.차일정용업알배남서사타정납,개위랍양두포납,환자미재출현추휵.
A 71-year-old woman received an Ⅳ infusion of imipenem-cilastatin sodium 0.5 g every 8 hours for suspicious hospital-acquired infection.On day 3,the patient suddenly developed convulsion,opisthotonos,and trismus complicated within unconsciousness and shortness of breath.The symptoms lasted 2～3 minutes and this attack was relieved spontaneously without any treatment.About 15 minutes later,the above symptoms recurred and,1 ～ 2 minutes later,she returned to normal status spontaneously.About 75 minutes and 2 hours later,the symptoms reappeared respectively lasting for 3-5 minutes and both diazepam and Xingnaojing(醒脑静) were given.About 50 minutes after the fourth seizure,the above-mentioned attack recurred and phenobarbitone was changed to an Ⅳ infusion of sodium valproate 400 mg via pump due to poor effect.About one hour later,the patient fell asleep quietly.The next day,imipenem-cilastatin sodium was discontinued and switched to latamoxef sodium and she did not experienced seizure anymore.