CAJ | 학술논문

目的：探讨右美托咪啶复合丁丙诺啡用于术后静脉P C A的安全性及效果。方法60例择期大手术后患者随机分为右美托咪啶组和丁丙诺啡组两组(n=30)，术后右美托咪啶组以右美托咪啶2μg/kg和丁丙诺啡6μg/kg加盐水至100ml行术后静脉PCA，丁丙诺啡组以丁丙诺啡12μg/kg加盐水至100ml行术后静脉PCA。观察并记录两组的镇痛效果及副作用并进行统计学分析。结果右美托咪啶组较单纯丁丙诺啡组镇痛效果更好，副作用少。结论右美托咪啶组复合丁丙诺啡用于术后静脉PCA效果确切，可减少丁丙诺啡用量和并发症。
목적：탐토우미탁미정복합정병낙배용우술후정맥P C A적안전성급효과。방법60례택기대수술후환자수궤분위우미탁미정조화정병낙배조량조(n=30)，술후우미탁미정조이우미탁미정2μg/kg화정병낙배6μg/kg가염수지100ml행술후정맥PCA，정병낙배조이정병낙배12μg/kg가염수지100ml행술후정맥PCA。관찰병기록량조적진통효과급부작용병진행통계학분석。결과우미탁미정조교단순정병낙배조진통효과경호，부작용소。결론우미탁미정조복합정병낙배용우술후정맥PCA효과학절，가감소정병낙배용량화병발증。
Objective To study the security and efficacy of postoperative patient-control ed venous analgesia with dexmedetomidine al ying buprenorphine. Methods 60 patients undergoing a elective capital operation were randomly divided into tow groups: dexmedetomidine group (Group D) and buprenorphine group (Group B ) (n=30). Al the patients received either dexmedetomidine2μg/kg and buprenorphine 6μg/kg (Group D)or buprenorphine 12μg/kg (Group B) adding sodium chloride injection to 100ml used to postoperative patient-control ed venous analgesia. The effects on the pain and the side-effects were recorded to make a statistical analysis of. Results The analgesia effect in dexmedetomidine group was significant better than in buprenorphine group and the incidence of side-effects lower. Conclusion Dexmedetomidine al yingbuprenorphine can be used effectively and safely to postoperative patient-control ed venous analgesia. And it could decrease the dose of buprenorphine.