CAJ | 학술논문

目的比较局部枸椽酸钠抗凝法与肝素抗凝法在CRRT中的应用效果.方法将我院2011年11月至2012年12月行CRRT治疗的126例患者随机分为两组,肝素抗凝组患者采用常规肝素抗凝方式治疗,局部枸椽酸钠抗凝组患者采用局部枸椽酸钠抗凝方式治疗.结果治疗后局部枸椽酸钠抗凝组患者未出现高钠血症和代谢性碱中毒情况;治疗后肝素抗凝组患者的体内钙离子浓度明显下降,局部枸椽酸钠抗凝组明显上升,两组比较差异有统计学意义(P＜0.05).结论在CRRT治疗中,局部枸椽酸钠抗凝比常规肝素抗凝更有效、更安全.
목적 비교국부구연산납항응법여간소항응법재CRRT중적응용효과.방법 장아원2011년11월지2012년12월행CRRT치료적126례환자수궤분위량조,간소항응조환자채용상규간소항응방식치료,국부구연산납항응조환자채용국부구연산납항응방식치료.결과 치료후국부구연산납항응조환자미출현고납혈증화대사성감중독정황;치료후간소항응조환자적체내개리자농도명현하강,국부구연산납항응조명현상승,량조비교차이유통계학의의(P＜0.05).결론 재CRRT치료중,국부구연산납항응비상규간소항응경유효、경안전.
Objective To compare the clinical effects of regional citrate anticoagulation with heparin sodium anticoagulation method in the application of continuous renal replacement therapy (CRRT).Methods In our hospital from November 2011 to December 2012,126 cases of C RRT were randomly divided into 2 groups,namely regional citrate anticoagulation group and heparin group.Heparin group was treated with conventional heparin anticoagulation therapy,regional citrate anticoagulation group was treated by regional citrate anticoagulation treatment.Results After treatment of regional citrate anticoagulation group patients did not appear hypernatremia and metabolic alkalosis; after treatment with heparin patients with total body calcium concentration decreased significantly,regional citrate anticoagulation group increased obviously.With comparison of the two groups,the difference was statistically significant (P＜0.05).Conclusion In the treatment of CRRT,regional citrate anticoagulation is more effective and safer than heparin anticoagulation