CAJ | 학술논문

在卫生领域巨大进步,在器官移植、生物材料植入等技术开展的同时,明显增加了曲霉菌感染危险人群,结果是侵袭性肺部曲霉菌病在令人惶恐的增加.高危人群包括:造血干细胞移植与实体器官移植的接受者,血液恶性肿瘤,获得性免疫缺陷病,免疫抑制剂治疗以及COPD激素治疗、糖尿病控制不良患者等.此外,虽然高级生命支持手段提高了危重患者的生存率,但同时增加了这部分患者继发侵袭性机会致病菌感染的风险.
재위생영역거대진보,재기관이식、생물재료식입등기술개전적동시,명현증가료곡매균감염위험인군,결과시침습성폐부곡매균병재령인황공적증가.고위인군포괄:조혈간세포이식여실체기관이식적접수자,혈액악성종류,획득성면역결함병,면역억제제치료이급COPD격소치료、당뇨병공제불량환자등.차외,수연고급생명지지수단제고료위중환자적생존솔,단동시증가료저부분환자계발침습성궤회치병균감염적풍험.
Major advances in healthcare have led to an unwelcome increase in invasive pulmonary aspergillosis largely because of the increasing size of the population at risk.This population includes recipient of hematopoietic stem cell transplants and solid organ transplants,patients with hematological malignancies,patients infected with human immunodeficiency virus developing acquired immunodeficiency syndrome,and patients receiving immunosuppressive treatment.Furthermore,the use of high-grade supportive care in severe and life-threatening diseases has improved survival,but has created a demographic shift in hospital and ICU populations.