CAJ | 학술논문

肥胖症的发病率在过去10年中几乎增加了1倍，而肥胖及其并发症所带来的直接或间接耗费约占国家卫生经费的10%。除心血管疾病等并发症外，近年来越来越多的研究结果发现，肥胖对男性、女性及雄、雌性实验鼠的生殖系统均有明显的负面效应。如肥胖可增加男性患前列腺癌的风险，并可引起性功能和精液质量的下降；对女性而言，肥胖可增加患多囊卵巢综合征的风险、并可引起生育力和卵细胞质量的下降；此外，肥胖还对儿童青少年的生长发育带来极大的危害。综述肥胖对生殖内分泌代谢、生殖器官形态学、性功能及生殖细胞发育等方面的影响。
비반증적발병솔재과거10년중궤호증가료1배，이비반급기병발증소대래적직접혹간접모비약점국가위생경비적10%。제심혈관질병등병발증외，근년래월래월다적연구결과발현，비반대남성、녀성급웅、자성실험서적생식계통균유명현적부면효응。여비반가증가남성환전렬선암적풍험，병가인기성공능화정액질량적하강；대녀성이언，비반가증가환다낭란소종합정적풍험、병가인기생육력화란세포질량적하강；차외，비반환대인동청소년적생장발육대래겁대적위해。종술비반대생식내분비대사、생식기관형태학、성공능급생식세포발육등방면적영향。
The occurrence of obesity increased almost two folds in the last decade,meanwhile the expense exhausted directly or indirectly by obesity and its complications reached about 10% of the overall state’s health expenditures. Besides its cardiovascular complications, obesity has significant negative effects on the reproductive system of both men and women,which was confirmed by animal experiments in male and female rodents. Obesity is a risk factor of prostatic cancer,sexual dysfunction, and the declined sperm quality, in males. Obesity is a risk factor of PCOS in females, the declined oocytes quality, and lowered fertile ability. Moreover,obesity has some severe detriments on the growth and development of children and teenagers. In this review,we elucidated the effects of obesity on reproductive endocrinology and metabolism,morphology of reproductive organs,sexual ability,and development of reproductive cells.