CAJ | 학술논문

卵巢过度刺激综合征（OHSS）是一种外源性或内源性促性腺激素所致的综合征。主要与使用外源性促性腺激素有关，偶见于使用氯米芬促排卵者，自然周期妊娠者较罕见。近年来，随着无排卵型不孕症发病率的逐年增高，在体外受精-胚胎移植（IVF-ET）中，控制性超促排卵是必要步骤。OHSS渐渐成为辅助生殖技术（ART）最常见最具潜在危险的并发症。其不但影响胚胎着床发育，严重者还会危及患者生命。综述近几年来OHSS发病机制、临床表现、预防及治疗等方面的研究现状。
란소과도자격종합정（OHSS）시일충외원성혹내원성촉성선격소소치적종합정。주요여사용외원성촉성선격소유관，우견우사용록미분촉배란자，자연주기임신자교한견。근년래，수착무배란형불잉증발병솔적축년증고，재체외수정-배태이식（IVF-ET）중，공제성초촉배란시필요보취。OHSS점점성위보조생식기술（ART）최상견최구잠재위험적병발증。기불단영향배태착상발육，엄중자환회위급환자생명。종술근궤년래OHSS발병궤제、림상표현、예방급치료등방면적연구현상。
Ovarian hyperstimulation syndrome (OHSS) is an exogenous or endogenous gonadotropin-induced syndrome. OHSS is associated mainly with exogenous gonadotropin,occasionally with Clomiphene,rarely with the natural cycles of pregnancy. In recent years,with the increasing incidence of anovulatory infertility,the controlled ovarian hyperstimulation becomes a necessary step in in vitro fertilization and embryo transfer. OHSS gradually became one of the most common complications with potentially high-dangerous in assisted reproductive technology. OHSS affects embryo implantation and embryo development, and it could be fatal in some severe cases. The research progress on the pathogenesis,clinical manifestations,prevention and treatment of OHSS were discussed in this review.