中华医学超声杂志（电子版）
中華醫學超聲雜誌（電子版）
중화의학초성잡지（전자판）
CHINESE JOURNAL OF MEDICAL ULTRASOUND(ELECTRONICAL VISION)
2013年
11期
903-906
,共4页
李娟%杨斌%傅宁华
李娟%楊斌%傅寧華
리연%양빈%부저화
甲状旁腺功能亢进%继发性%超声检查%多普勒%彩色%消融技术
甲狀徬腺功能亢進%繼髮性%超聲檢查%多普勒%綵色%消融技術
갑상방선공능항진%계발성%초성검사%다보륵%채색%소융기술
Hyperparathyroidism,Secondary%Ultrasonography,Doppler,color%Ablation techniques
目的：应用彩色多普勒超声对慢性肾功能衰竭继发甲状旁腺功能亢进超声引导下注射无水乙醇治疗的疗效进行观察评价。方法2011年1月至2013年5月南京军区南京总医院53例慢性肾功能衰竭继发甲状旁腺功能亢进患者，对患者增生的甲状旁腺腺体于超声引导下注射无水乙醇治疗。彩色多普勒超声观察治疗前后甲状旁腺腺体回声、体积和血供变化。采用独立样本t检验比较患者治疗前后血清PTH浓度、甲状旁腺体积差异。结果治疗前，53例患者甲状旁腺体积为（5.28±0.84）cm3，肿大的甲状旁腺均呈均匀低回声，血供丰富，血清PTH浓度为（1041.6±37.1）ng/L；治疗后甲状旁腺体积为（3.93±0.67）cm3，与治疗前比较差异无统计学意义，甲状旁腺回声多增强，血供减少，血清PTH浓度为（509.2±27.6）ng/L，较治疗前降低，且差异有统计学意义（t=3.792，P＜0.05）。结论彩色多普勒超声引导下注射无水乙醇对继发性甲状旁腺功能亢进的治疗效果显著，并能及时观察疗效，具有重要价值。
目的：應用綵色多普勒超聲對慢性腎功能衰竭繼髮甲狀徬腺功能亢進超聲引導下註射無水乙醇治療的療效進行觀察評價。方法2011年1月至2013年5月南京軍區南京總醫院53例慢性腎功能衰竭繼髮甲狀徬腺功能亢進患者，對患者增生的甲狀徬腺腺體于超聲引導下註射無水乙醇治療。綵色多普勒超聲觀察治療前後甲狀徬腺腺體迴聲、體積和血供變化。採用獨立樣本t檢驗比較患者治療前後血清PTH濃度、甲狀徬腺體積差異。結果治療前，53例患者甲狀徬腺體積為（5.28±0.84）cm3，腫大的甲狀徬腺均呈均勻低迴聲，血供豐富，血清PTH濃度為（1041.6±37.1）ng/L；治療後甲狀徬腺體積為（3.93±0.67）cm3，與治療前比較差異無統計學意義，甲狀徬腺迴聲多增彊，血供減少，血清PTH濃度為（509.2±27.6）ng/L，較治療前降低，且差異有統計學意義（t=3.792，P＜0.05）。結論綵色多普勒超聲引導下註射無水乙醇對繼髮性甲狀徬腺功能亢進的治療效果顯著，併能及時觀察療效，具有重要價值。
목적：응용채색다보륵초성대만성신공능쇠갈계발갑상방선공능항진초성인도하주사무수을순치료적료효진행관찰평개。방법2011년1월지2013년5월남경군구남경총의원53례만성신공능쇠갈계발갑상방선공능항진환자，대환자증생적갑상방선선체우초성인도하주사무수을순치료。채색다보륵초성관찰치료전후갑상방선선체회성、체적화혈공변화。채용독립양본t검험비교환자치료전후혈청PTH농도、갑상방선체적차이。결과치료전，53례환자갑상방선체적위（5.28±0.84）cm3，종대적갑상방선균정균균저회성，혈공봉부，혈청PTH농도위（1041.6±37.1）ng/L；치료후갑상방선체적위（3.93±0.67）cm3，여치료전비교차이무통계학의의，갑상방선회성다증강，혈공감소，혈청PTH농도위（509.2±27.6）ng/L，교치료전강저，차차이유통계학의의（t=3.792，P＜0.05）。결론채색다보륵초성인도하주사무수을순대계발성갑상방선공능항진적치료효과현저，병능급시관찰료효，구유중요개치。
Objective To observe and evaluate the effect of ultrasound guided percutaneous ethanol injection for hyperparathyroidism secondary to chronic renal failure. Methods Fifty-three patients with secondary hyperparathyroidism in Nanjing General Hospital Military Command from January 2011 to May 2013 were treated by percutaneous ethanol injection. The echogenicity, size and blood supply of parathyroid glands were observed by color Doppler ultrasound before and after treatment. Parathyroid hormone (PTH) and volumes of parathyroid glands were analyzed and compared with non-paired t test. Results Before treatment, the parathyroid gland volume was (5.28±0.84) cm3. The enlarged parathyroid glands had homogeneous hypoechogenicity and abundant blood supply, and the PTH was (1041.6±37.1) ng/L. After treatment, the size of solitary parathyroid gland was (3.93±0.67) cm3 which did not change significantly compared with that before treatment. The echogenicity of parathyroid glands enhanced and blood supply decreased after injection ethanol into solitary parathyroid. PTH [(509.2±27.6) ng/L] decreased obviously (t=3.792, P < 0.05). Conclusion Color Doppler ultrasound guided percutaneous injection of ethanol has an important role in the treating of secondary hyperparathyroidism and the curative effect can be observed timely.
