检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2013年
23期
3140-3141
,共2页
非小细胞肺癌%放疗%化疗%手术治疗
非小細胞肺癌%放療%化療%手術治療
비소세포폐암%방료%화료%수술치료
non - small cell lung cancer%radiotherapy%chemotherapy%surgery
目的:比较非小细胞肺癌(NSCLC)手术与非手术治疗的临床疗效和预后。方法将116例 NSCLC患者根据是否予以手术治疗分为手术组和非手术组,每组各58例。手术组予以手术根除性切除联合放疗和化疗治疗;非手术组则只运用放疗和化疗治疗。结果手术组总体有效率为79.31%,显著优于非手术组的24.13%,差异有统计学意义(P<0.05);且毒副作用的发生率均低于非手术组,差异有统计学意义(P<0.05);手术组的局部复发率、远处转移率、局部复发并远处转移率均明显低于非手术组,且1、3、5年的生存率明显升高,差异均有统计学意义(P<0.05)。结论以手术为主的多学科综合治疗方式可提高 NSCLC 患者生存率,降低毒副作用、局部复发和肿瘤转移。
目的:比較非小細胞肺癌(NSCLC)手術與非手術治療的臨床療效和預後。方法將116例 NSCLC患者根據是否予以手術治療分為手術組和非手術組,每組各58例。手術組予以手術根除性切除聯閤放療和化療治療;非手術組則隻運用放療和化療治療。結果手術組總體有效率為79.31%,顯著優于非手術組的24.13%,差異有統計學意義(P<0.05);且毒副作用的髮生率均低于非手術組,差異有統計學意義(P<0.05);手術組的跼部複髮率、遠處轉移率、跼部複髮併遠處轉移率均明顯低于非手術組,且1、3、5年的生存率明顯升高,差異均有統計學意義(P<0.05)。結論以手術為主的多學科綜閤治療方式可提高 NSCLC 患者生存率,降低毒副作用、跼部複髮和腫瘤轉移。
목적:비교비소세포폐암(NSCLC)수술여비수술치료적림상료효화예후。방법장116례 NSCLC환자근거시부여이수술치료분위수술조화비수술조,매조각58례。수술조여이수술근제성절제연합방료화화료치료;비수술조칙지운용방료화화료치료。결과수술조총체유효솔위79.31%,현저우우비수술조적24.13%,차이유통계학의의(P<0.05);차독부작용적발생솔균저우비수술조,차이유통계학의의(P<0.05);수술조적국부복발솔、원처전이솔、국부복발병원처전이솔균명현저우비수술조,차1、3、5년적생존솔명현승고,차이균유통계학의의(P<0.05)。결론이수술위주적다학과종합치료방식가제고 NSCLC 환자생존솔,강저독부작용、국부복발화종류전이。
Objective To compare clinical efficacy and prognosis between surgical and non-surgical treatment in patients with non-small cell lung cancer (NSCLC) .Methods A total of 116 cases with NSCLC were randomly di-vided into surgical treatment group and non surgical treatment group ,fifty eight cases in each group .Surgical therapy group received surgery ,chemotherapy and radiotherapy ;while the non-surgical group only received chemotherapy .Re-sults Overall effective in combined therapy group was 79 .31% ,which significantly higher than non surgical treat-ment group with 24 .13% (P< 0 .05) ,and the rate of toxic and side effects were lower than the non-surgical treatment group(P< 0 .05) .Local recurrence ,distant metastasis rate ,and the local recurrence combined with distant metastasis were significantly lower than the surgery group ,and the 1 ,3 ,5-year survival rates were significantly higher than the non-surgical group(P< 0 .05) .Conclusion Surgical treatment of NSCLC patients can improve survival rates ,reduce toxicity ,local recurrence and tumor metastasis .