CAJ | 학술논문

目的：了解深圳地区2011～2013年住院患者产超广谱β内酰胺酶（ESBLs）大肠埃希菌的感染情况，为临床治疗及预防产 ESBLs 大肠埃希菌引起的感染提供警示。方法对2011年5月至2013年3月感染大肠埃希菌的住院患者采集临床资料，进行药敏试验，并进行统计学分析。结果深圳市宝安区西乡人民医院在2011年5月至2013年3月住院患者中检出大肠埃希菌328株，ESBLs 158株，阳性率为48．17％，产 ESBLs 大肠埃希菌检出较多的科室为泌尿外科28株，17．72％；标本最多的为尿液71株，占44．94％。 ESBLs 阳性菌株中，tem 基因检出85例，检出率53．80％，其中 TEM-1检出63例，占74．12％。产 ESBLs 大肠埃希菌对各种抗菌药物均产生耐药。结论产 ESBLs 大肠埃希菌耐药明显，tem 基因型以 TEM-1为主。
목적：료해심수지구2011～2013년주원환자산초엄보β내선알매（ESBLs）대장애희균적감염정황，위림상치료급예방산 ESBLs 대장애희균인기적감염제공경시。방법대2011년5월지2013년3월감염대장애희균적주원환자채집림상자료，진행약민시험，병진행통계학분석。결과심수시보안구서향인민의원재2011년5월지2013년3월주원환자중검출대장애희균328주，ESBLs 158주，양성솔위48．17％，산 ESBLs 대장애희균검출교다적과실위비뇨외과28주，17．72％；표본최다적위뇨액71주，점44．94％。 ESBLs 양성균주중，tem 기인검출85례，검출솔53．80％，기중 TEM-1검출63례，점74．12％。산 ESBLs 대장애희균대각충항균약물균산생내약。결론산 ESBLs 대장애희균내약명현，tem 기인형이 TEM-1위주。
Objective To understand the status of effection with e .coli producing extended spectrum β lacta-mase(ESBLs) about the hospitalized patients in Shenzhen city ,in order to provide basis for clinical treatment and pre-vention .Methods The clinical data and drug sensitive test result of the hospitalized patients infected with e .coli were collected and analyzed from May in 2011 to March in 2013 .Results Between the results in our hospital in hospital-ized patients ,detected 328 cases of e .coli ,ESBLs158 example ,the positive rate of 48 .17% ,produce ESBL e .coli de-tected more department of urology (28 cases ,17 .72% ) ,the largest specimens was urine(71 cases ,44 .94% ) ;During the ESBLs positive strains ,TEM genes detected in 85 cases ,the positive rate of 53 .80% ,of which TEM-1 detected in 63 cases ,accounting for 74 .12% ;were resistant to various antibiotics .Conclusion E .coli producing ESBLs resist-ance is apparent ,should be took seriously .