CAJ | 학술논문

目的：探讨凝血、抗凝血指标和血小板等有关指标的改变与复发性流产发生的意义。方法选择30例正常足月妊娠妇女和50例复发性流产疾病患者，对活化部分凝血活酶时间（APTT ）、凝血酶原时间（PT ）、纤维蛋白原（FIB）、凝血酶时间（TT ）和抗凝血酶Ⅲ（AT Ⅲ）以及血小板计数（PLT ）进行检测和统计分析。结果复发性流产疾病组与正常足月妊娠组相比，PT 、APTT 、FIB 、AT Ⅲ、PLT 、TT 差异均无统计学意义（P＞0．05）；D-二聚体两组差异有统计学意义（P＜0．05）。结论联合检测凝血、抗凝血指标说明复发性流产疾病孕妇比正常孕妇具有更高的凝血状态，有血栓形成倾向。
목적：탐토응혈、항응혈지표화혈소판등유관지표적개변여복발성유산발생적의의。방법선택30례정상족월임신부녀화50례복발성유산질병환자，대활화부분응혈활매시간（APTT ）、응혈매원시간（PT ）、섬유단백원（FIB）、응혈매시간（TT ）화항응혈매Ⅲ（AT Ⅲ）이급혈소판계수（PLT ）진행검측화통계분석。결과복발성유산질병조여정상족월임신조상비，PT 、APTT 、FIB 、AT Ⅲ、PLT 、TT 차이균무통계학의의（P＞0．05）；D-이취체량조차이유통계학의의（P＜0．05）。결론연합검측응혈、항응혈지표설명복발성유산질병잉부비정상잉부구유경고적응혈상태，유혈전형성경향。
Objective To investigate the relationship between the coagulation function and thrombosis in pa-tients with recurrent spontaneous abortion (RSA) .Methods The prothrombin time(PT ) ,activated partial thrombo-plastin time(APTT ) ,thrombin time(TT ) ,fibrinogen(FIB) ,antithrombin Ⅲ (AT Ⅲ ) ,platelet count(PLT ) were test-ed and analyzed in 30 normal pregnant women in the third trimester and 50 pregnant women with RSA .Results Compared with the normal pregnant women ,the levels of PT ,APTT ,FIB ,AT Ⅲ ,PLT ,TT in the pregnant women with spontaneous abortion disorders was no significont differences (P > 0 .05) ,D-dimer has significont differences(P< 0 .05) .Conclusion There are thrombophilia in pregnant women with spontaneous abortion disorders .