中国保健营养（中旬刊）
中國保健營養（中旬刊）
중국보건영양（중순간）
China Hwalth Care & nutrition
2013年
7期
24-25
,共2页
刘贤广%宿国波%李鑫%钱忠雪%周慧颖
劉賢廣%宿國波%李鑫%錢忠雪%週慧穎
류현엄%숙국파%리흠%전충설%주혜영
洛铂%顺铂%恶性胸腔积液
洛鉑%順鉑%噁性胸腔積液
락박%순박%악성흉강적액
Lobaplatin%Cisplatin%Malignant Pleural Effusion
目的：比较洛铂（LBP）或顺铂（DDP）治疗恶性胸腔积液的疗效。方法：对确诊为恶性胸腔积液的60例病人随机分为LBP组(n=30)和DDP组(n=30)，采用胸腔内注射治疗方法，LBP组注入洛铂，DDP组注入顺铂，比较两组间疗效和不良反应。结果：LBP组与DDP组疗效比较差异无统计学意义（P>0.05），在毒副作用方面，LBP组在白细胞减少、贫血、恶心呕吐发生率较DDP组低，差异有统计学意义（P﹤0.05）。结论：洛铂胸腔内注射治疗肺癌致恶性胸腔积液疗效与顺铂相当，毒副反应较轻。
目的：比較洛鉑（LBP）或順鉑（DDP）治療噁性胸腔積液的療效。方法：對確診為噁性胸腔積液的60例病人隨機分為LBP組(n=30)和DDP組(n=30)，採用胸腔內註射治療方法，LBP組註入洛鉑，DDP組註入順鉑，比較兩組間療效和不良反應。結果：LBP組與DDP組療效比較差異無統計學意義（P>0.05），在毒副作用方麵，LBP組在白細胞減少、貧血、噁心嘔吐髮生率較DDP組低，差異有統計學意義（P﹤0.05）。結論：洛鉑胸腔內註射治療肺癌緻噁性胸腔積液療效與順鉑相噹，毒副反應較輕。
목적：비교락박（LBP）혹순박（DDP）치료악성흉강적액적료효。방법：대학진위악성흉강적액적60례병인수궤분위LBP조(n=30)화DDP조(n=30)，채용흉강내주사치료방법，LBP조주입락박，DDP조주입순박，비교량조간료효화불량반응。결과：LBP조여DDP조료효비교차이무통계학의의（P>0.05），재독부작용방면，LBP조재백세포감소、빈혈、악심구토발생솔교DDP조저，차이유통계학의의（P﹤0.05）。결론：락박흉강내주사치료폐암치악성흉강적액료효여순박상당，독부반응교경。
Objective To compare the therapeutic effect and adverse reaction of lobaplatin and cisplatin for treatment of Malignant Pleural Effusion.Methods A total of 60 patients with Malignant Pleural Effusion were treated by the way of intrapleural injection.The patients were divided randomized into two groups:30 cases were injected lobaplatin (LBP group), 30 cases were injected cisplatin (DDP group).Results The clinical efficacy were not significantly different between two groups(P>0.05).The incidences of WBC reduction,hypohemia,sicchaisa and vomit were significant higher in DDP group than that in LBP group(P﹤0.05).Conclusion The treatment of Lobaplatin showed almost the same clinical efficacy compared to the therapy of cisplatin in treatment of malignant pleural effusion,but with less side effct.
