CAJ | 학술논문

目的：探讨尿N-乙酰-β-D-氨基葡萄糖苷酶（NAG）检测对早期肾损害的诊断价值及临床意义。方法分别对我院340例住院患者和40例健康体检者进行尿NAG、尿微量白蛋白（MALB）、β2-微球蛋白（β2-MG）、α1-微球蛋白（α1-MG）检测。结果340例住院患者中124例患者标本NAG检测结果显著高于健康对照组；87例患者标本β2-MG检测结果显著高于健康对照组；64例患者标本α1-MG检测结果显著高于健康对照组；46例患者标本MALB检测结果显著高于健康对照组。结论尿NAG检测对于早期肾损害的灵敏度优于尿β2-MG、尿α1-MG和尿MALB。对于临床早期发现患者肾损害有一定提示作用，值得临床推广。
목적：탐토뇨N-을선-β-D-안기포도당감매（NAG）검측대조기신손해적진단개치급림상의의。방법분별대아원340례주원환자화40례건강체검자진행뇨NAG、뇨미량백단백（MALB）、β2-미구단백（β2-MG）、α1-미구단백（α1-MG）검측。결과340례주원환자중124례환자표본NAG검측결과현저고우건강대조조；87례환자표본β2-MG검측결과현저고우건강대조조；64례환자표본α1-MG검측결과현저고우건강대조조；46례환자표본MALB검측결과현저고우건강대조조。결론뇨NAG검측대우조기신손해적령민도우우뇨β2-MG、뇨α1-MG화뇨MALB。대우림상조기발현환자신손해유일정제시작용，치득림상추엄。
Objective: To explore diagnostic value of urinary NAG in early renal injury . Methods: 340 cases in our hospital patients and 40 healthy subjects for urinary NAG, urinary albmin(MALB),β2-microglobulin(β2-MG),a1-microglobulin(a1-MG) detection. Results:In 340 cases of hospitalized patients, 120 patients specimens NAG test results were significantly higher than the healthy controls group; 87 patients specimensβ2-MG test results were significantly higher than the healthy controls group; 64 patients specimens a1-MG test results were significantly higher than the healthy controls group; 46 patients specimens MALB test results were significantly higher than the healthy control group. Conclusion: Urinary NAG detection sensitivity for early renal damage than urinary β2-MG, urinary a1-MG and urine MALB. For clinical renal damage in patients with early detection of certain suggestive, worthy of promotion .