CAJ | 학술논문

目的：探讨伊曲康唑在慢性阻塞性肺病并肺部真菌感染患者的临床效果。方法对照组在常规治疗的基础上加用两性霉素B治疗，观察组在常规治疗的基础上加用伊曲康唑治疗。比较两组治疗效果、不良反应发生情况。结果两组治疗总有效率、不良反应发生率差异无统计学意义。结论根据患者真菌感染类型，选择合适的抗菌药物，合理使用抗生素及激素，可有效治疗COPD患者继发肺部真菌感染。
목적：탐토이곡강서재만성조새성폐병병폐부진균감염환자적림상효과。방법대조조재상규치료적기출상가용량성매소B치료，관찰조재상규치료적기출상가용이곡강서치료。비교량조치료효과、불량반응발생정황。결과량조치료총유효솔、불량반응발생솔차이무통계학의의。결론근거환자진균감염류형，선택합괄적항균약물，합리사용항생소급격소，가유효치료COPD환자계발폐부진균감염。
Objective To study the clinical effect of itraconazole in the treatment of COPD patients compli-cated with pulmonary fungus infection. Methods On the basis of routine treatment, the control group was plus trea-ted with amphotericin B, and the observation group was given itraconazole. Their curative effect and adverse reactions were compared. Results There was no significant difference in total effective rate and adverse reactions between the two groups ( P>0. 05 ) . Conclusion According to the type of fungal infection, appropriate antimicrobial agents should be chosen, that can effectively treat the secondary pulmonary fungal infection in patients with COPD.