CAJ | 학술논문

为明确番鸭呼肠孤病毒弱毒疫苗在番鸭体内中和抗体消长规律，采用固定病毒稀释血清法，测定了经弱毒疫苗免疫后的雏番鸭不同时间其血清中和抗体效价。结果显示：疫苗注射1日龄雏番鸭，免疫后28 d部分鸭血清中出现抗体，35 d全部鸭血清中出现抗体；6个月抗体效价达高峰，有效免疫期在18个月以上。表明番鸭呼肠孤病毒弱毒疫苗诱导的中和抗体产生期较晚，但持续期长。
위명학번압호장고병독약독역묘재번압체내중화항체소장규률，채용고정병독희석혈청법，측정료경약독역묘면역후적추번압불동시간기혈청중화항체효개。결과현시：역묘주사1일령추번압，면역후28 d부분압혈청중출현항체，35 d전부압혈청중출현항체；6개월항체효개체고봉，유효면역기재18개월이상。표명번압호장고병독약독역묘유도적중화항체산생기교만，단지속기장。
To determine antibody response in the serum of muscovy ducks immunized with muscovy duck reovirusis (MDRV) alive vaccine ,the fluctuation of antibody titers was detected in the serum by fixed virus-serum dilutions method .The results showed that some muscovy ducks turned positive on antibody against MDRV after vaccination in 28th day ,while all of them appeared to be MDRV-antibody positive within 35 days ;the peak titer of the antibody showed at the 6th month after vaccination ,and the period of effective immunization could last over 18 months .The results told that there was a long delay between MDRV vaccination and antibody origin ,while the duration of antibody production was relatively long ,which provided scientific basis for immune procedure development .