CAJ | 학술논문

目的：研究介入法治疗对急性冠脉综合征患者血清 IL 6、MMP 9及 C反应蛋白的影响,了解介入治疗对于血管内皮的损伤以及炎症反应的影响。方法选取急性冠脉综合征患者42例,分别在手术前及手术后1 d、1周后测IL 6、MMP 9及C反应蛋白。选取身体健康者42例,对于 IL 6、MMP 9及C反应蛋白进行测定,与患者血清含量进行对比。结果手术前,术后1 d,术后1周患者血清 IL 6、MMP 9及C反应蛋白出现先上升,后下降的趋势,实验结果具有统计学意义。患者三种测量值均高于健康者(P<0.05)。结论急性冠脉综合征患者体内会产生炎症反应,介入法治疗后内皮损伤会造成炎症反应升高,经过一段时间之后,患者体内的炎症反应会下降。
목적：연구개입법치료대급성관맥종합정환자혈청 IL 6、MMP 9급 C반응단백적영향,료해개입치료대우혈관내피적손상이급염증반응적영향。방법선취급성관맥종합정환자42례,분별재수술전급수술후1 d、1주후측IL 6、MMP 9급C반응단백。선취신체건강자42례,대우 IL 6、MMP 9급C반응단백진행측정,여환자혈청함량진행대비。결과수술전,술후1 d,술후1주환자혈청 IL 6、MMP 9급C반응단백출현선상승,후하강적추세,실험결과구유통계학의의。환자삼충측량치균고우건강자(P<0.05)。결론급성관맥종합정환자체내회산생염증반응,개입법치료후내피손상회조성염증반응승고,경과일단시간지후,환자체내적염증반응회하강。
Objective To study the effect of interventional therapy on IL 6,MMP 9,and effect of C reactive protein in patients with acute coronary syndrome.Methods The IL 6,MMP 9,and C reactive protein in 42 patients with acute coronary syndrome were measured pre and post surgery and 42 subjects as controls.Results Compared with pre surgery,IL 6,MMP 9 and c re-active protein were increased postsurgery (P<0.05).IL 6,MMP 9 and C reactive protein in patients were higher than that in controls (P<0.05).Conclusion IL 6,MMP 9 and c reactive protein in patients with acute coronary syndrome and interventional therapy were increased and related to endothelial inj ury after interventional treatment.