CAJ | 학술논문

目的：探讨正常人唾液皮质醇、血浆皮质醇和24 h尿游离皮质醇三者之间的相关性。方法选择30例健康受试者同时检测唾液皮质醇、血浆皮质醇和24 h尿游离皮质醇。男子组和女子组各15例。采用化学发光技术测定，唾液标本采用唾液收集器收集，血标本为血浆，24 h尿液标本用硼酸防腐。结果唾液皮质醇和血浆、24 h尿液皮质醇在正常男女组之间均无显著性差异（P＞0．05），唾液皮质醇与血浆皮质醇（r＝0．91）、唾液皮质醇与24 h尿游离皮质醇（r＝0．95），均存在显著的相关性。结论唾液皮质醇可作为库欣氏综合征的筛查指标。
목적：탐토정상인타액피질순、혈장피질순화24 h뇨유리피질순삼자지간적상관성。방법선택30례건강수시자동시검측타액피질순、혈장피질순화24 h뇨유리피질순。남자조화녀자조각15례。채용화학발광기술측정，타액표본채용타액수집기수집，혈표본위혈장，24 h뇨액표본용붕산방부。결과타액피질순화혈장、24 h뇨액피질순재정상남녀조지간균무현저성차이（P＞0．05），타액피질순여혈장피질순（r＝0．91）、타액피질순여24 h뇨유리피질순（r＝0．95），균존재현저적상관성。결론타액피질순가작위고흔씨종합정적사사지표。
Objective To investigate the correlation among normal salivary cortisol ,plasma cortisol and 24-hour urine free cortisol of healthy human beings .Methods A total of 30 healthy subjects were selected and equally divided into male group and female group . The levels of salivary cortisol ,plasma cortisol and 24-hour urine free cortisol were detected by chemiluminescence technique .Salivary specimens were collected using salivary collector .Blood specimens were blood plasma .24-hour urine specimens were antisepticized by using boric acid .Results The levels of salivary cortisol ,plasma cortisol and 24-hour urine free cortisol showed no significant differ-ence between male group and female group (P>0.05).The correlation analysis results showed that the levels of three kinds of cortisol were highly related(P<0.001).Conclusions Salivary cortisol testing can be used as screening indicator of Cushing ’s syndrome.